Buy Advantage Multi (Advocate) Extra Large Dogs 55.1-88 lbs (Blue) Online at Lowest Price with Free Shipping at easyvetsupplies.com. Advantage Multi is a broad-spectrum, monthly spot-on treatment for dogs. It helps kill and control fleas, gastrointestinal worms (hookworm, roundworm, and whipworm), sarcoptic mange, and demodicosis in canines. For small and medium dogs - one spot between the shoulder blades is enough. For larger dogs – Apply at 3 to 4 spots across the backbone until the base of the tail. Place the mouth of the open tube on the skin and squeeze out the entire content of the tube.