Frontline Plus For Dog In-Depth Review. Fleas, ticks, and lice often become painful for the pet dogs and cats and their owners. Ranging from flea collars to topical treatment to chewable substances, there are different effective methods of killing fleas and ticks. There are also too many varieties of flea and pest control products from different brands. Among all of them, Frontline Plus stands apart with its popularity and highly effective formula. A quick look at the Frontline Plus benefits and drawbacks Since no great product can be completely free from the drawbacks, an honest review must showcase these negative areas as well. Let's have a quick look at the Frontline Plus key benefits and drawbacks before coming with more elaborate points.