Emerging Natural Anti Inflammatory Compounds 
                     Emerging Natural Anti 
Inflammatory Compounds
Sources, Benefits, and Future Applications (2024–
2025) 
Introduction to 
Inflammation
• Inflammation: Immune response triggered by 
injury/infection
• Two types
• Acute: Short-term, tissue repair
• Chronic: Persistent, linked to diseases
• Recent discoveries: NLRP3 inflammasome, gut 
brain axis interact
Emerging Natural Anti-
Inflammatory Compounds
Categories of Natural Anti-
Inflammatory Chemicals
• Polyphenols: Curcumin, resveratrol, 
quercetin, EGCG
• Terpenoids: Gingerols, boswellic acids
• Alkaloids & Capsaicinoids: Capsaicin
• Flavonoids: Luteolin, apigenin
Advantages Over NSAIDs & 
Regulatory Overview
• NSAIDs effective but have side effects: Renal, 
cardiovascular, GI ulcers
• Shift towards plant-based bioactives: Safer, 
fewer side effects, multifunctional
• Regulatory bodies
• FDA: Approves natural compounds as 
supplements
• FSSAI (India): Regulates herbal supplements, 
allows curcumin with compliance
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