Professional Survey Report On Protein Expression Market: 2022
                     MarketsandMarkets 
Presents
Protein Expression Market worth $5.4 billion by 2027
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Browse 347 market data Tables and 47 Figures spread through 327 Pages and in-depth TOC on 
The report "Protein Expression Market by Type (E.Coli, Mammalian, CHO, HEK 293, Insect, Pichia, 
Cell-free), Products (Reagents, Vectors, Competent Cells, Instruments, Service), Application 
(Therapeutic, Industrial), End User, and Region - Global Forecast to 2027", is expected to reach 
USD 5.4 billion by 2027 from an estimated USD 2.9 billion in 2022 at a CAGR of 13.3%. 
Factors such as the increasing incidence of chronic diseases, increasing research activities on 
recombinant-based protein expression, growth in the life sciences and biopharmaceutical 
industries, as well as the availability of funding for protein-based research. However, the high 
cost of protein expression reagents and instruments is expected to restrain the growth of this 
market.
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Objectives of the Study:
• The Mammalian expression system segment accounted for the largest share in the Protein 
Expression Market
Based on system type, the protein expression market is segmented into 
mammalian cell expression systems, prokaryotic expression systems, insect cell 
expression systems, yeast expression systems, cell-free expression systems, and 
algal-based expression systems. The large share of this segment can be owed to 
the low cost and ease of use of mammalian cell expression systems.
• The Research applications subsegment accounted for the largest share of the application 
segment
Based on application, the protein expression market is segmented into therapeutic, 
research and industrial applications. The therapeutic applications segment 
accounted for the largest share of the global protein expression market. An 
increase in protein-based research and the rising prevalence of chronic diseases 
across the globe are responsible for a large share of this market.
• The Pharmaceutical and Biotechnology companies subsegment accounted for the largest 
share of the application
• North America is the largest region and Asia Pacific is the fastest-growing region
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This report categorizes the Protein Expression market into the following segments and 
subsegments:
Protein Expression Market, by System Type
• Mammalian cell expression systems
• Prokaryotic expression systems
• Insect cell expression systems
• Yeast expression systems
• Cell-free expression systems
• Algal-based expression systems   
Protein Expression Market, by Application
• Therapeutic
• Research
• Industrial
Protein Expression Market, by End user
• Pharmaceutical and Biotechnology companies
• Contract Research Organizations and Contract Development and Manufacturing Organizations 
(CROs and CDMOs)
• Academic Research Institutes
• Other End Users
Key players in the Protein Expression market include Thermo Fisher Scientific Inc. (US), 
Merck KGaA (Germany), GenScript Biotech Corporation (US), Agilent Technologies Inc. 
(US), Danaher Corporation (US), Sartorius AG (Germany), Takara Bio Inc. (Japan), Bio-Rad 
Laboratories Inc. (US), Lonza Group AG (Switzerland), Promega Corporation (US), New 
England Biolabs (US), and Oxford Expression Technologies Ltd. (UK) and Among others.
Companies Insight
Thermo Fisher Scientific Inc. (US) is the largest player in the protein expression market. Factors 
such as strong suite of expression vectors, reagents, competent cells, and instruments, as well as 
protein expression services are highly attributing to the large share of this company. Owing to its 
strong sales and distribution network, the company has a significant global footprint. 
Additionally, presence of multiple production sites at majority geographic locations gives the 
company an edge over other players in the protein expression market.
Agilent Technologies, Inc. (US) is a leader in providing instruments, software, services, and 
consumables for laboratory operations. The company has a broad portfolio of protein expression 
products, such as competent cells, expression vectors, kits for protein purification, and 
transfection. The biopharma companies and academia highly rely on Agilent for its protein 
expression products. Besides, in 2021, the company experienced double-digit growth in its 
revenue from protein expression as compared to 2020. Also, the company continues to invest 
highly in R&D for its growth. In 2021, the company invested around USD 358 million.
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