Stem cell study holds out promise for kidney disease
                     Stem Cell Study Holds out 
Promise for Kidney Disease
Stem Cell Research
 Days of clinical research 
empower scientists to discover 
novel methods using stem cells 
to develop more humanlike tiny 
kidneys. This is something, 
which is not as new to us as we 
had enough of such research-
based organ development for 
kidney impairments earlier as 
well.

More the number of new 
methods to investigate 
etiologies of kidney disorders 
are developed, more 
prospective and fruitful results 
we can expect.
Why Stem-Cell Based Research Is So 
Promising?
As far as tissue engineering is 
concerned, they turn out to be a 
promising therapeutic approach to 
facilitate kidney replacement and 
regeneration therapies. So, developing 
the method for any kidney tissues 
depends largely on comprehensive 
insights into kidney formations, which 
can contribute to mimic the process in 
cell culture in the lab.
With a better data through stem cell 
research, it is likely to receive more 
precise and accurate information 
about the kidneys, enabling 
researchers to develop a better 
functional kidney.
Why Stem-Cell Based Research Is So 
Promising?
 This is another feat of 
stem cells, which raises a 
prospective result for us 
to avoid renal failure and 
its debilitating 
consequences. Kidney 
disorder or failure is a 
growing concern for 
American adults as it 
affects about 30 million 
citizens among them or 
about 15% of the total 
population. 
 The number of affected 
patients is higher than 
those patients suffering 
from breast cancer and 
prostate cancer combined.
Why Stem-Cell Based Research Is So 
Promising?
 Since, the mini kidney 
regeneration is a 
hope for us to replace 
damaged kidney, 
there is another 
study, proving to be a 
prospective method 
to repair damaged 
kidneys too.
Kidney Repair Requisite
 Our kidneys are a pair of 
important organs that 
helps discharge waste 
products from the bodies, 
while filtering and 
cleaning our blood to 
detoxify it of all the waste 
products. Unlike skin, 
kidneys have very little 
capacity to heal by 
themselves to repair its 
scar or damage. 
 On failure to exert this key 
function, the damaged 
kidneys in the patients 
worsen their conditions, 
pushing them to suffer 
from end stage kidney 
disease. 
Kidney Repair Requisite
  The condition leaves the 
patients with no options, 
except dialysis and kidney 
transplant.
 But, a novel therapy is a 
possibility that may help to 
repair damaged kidneys 
and help patients avoid 
these costly treatment 
options like dialysis and 
organ transplant.
Hope for the Kidney Patients
 Kidneys have some cells with 
the characterization of a 
regenerative capacity. This fact 
has been brought to the light by 
scientists in Italy. These cells 
with transcription factors CD133 
are a type of molecules, which 
have the capacity to sustain 
renal injuries and regenerate 
various kidney cells.

Scientists at the University of 
Torino wanted to work on these 
cells and wanted to gauge how 
these molecules worked to 
further the process of tissue 
repair in damaged kidneys.
The Process of the Research
 The scientists used a 
chemotherapy drug cisplatin, 
used for the treatment of 
cancers. In addition, the drug 
is supposed to affect the 
functions of kidneys too in at 
least one third of the patients. 
 It was found that CD133 
played a key role in helping 
recover damaged kidneys in 
the patients, while preventing 
the progenitor cells of kidneys 
from aging. This is important 
to help repair damaged 
kidneys in the future.
The Process of the Research
 This is helpful for the further 
research of kidney disease, so 
that with infusions of CD133 
molecules, it will be possible to 
help patients with damaged 
kidney repair one day. 
 Although the process is 
effective for the treatment of 
last stage of kidney ailments, it 
is hopeful that the process can 
help people with an early stage 
of disease also and remove the 
complications completely.
About CordlifeIndia
 CordlifeIndia provides services like 
stem cell banking, stem cell preservation for 
baby’s secure life.
 We provide reliable healthcare solutions through 
innovation, technological advancement and 
commitment to quality .
 We help people live healthier, happier and longer.
References:
 https://www.cordlifeindia.com/blog/stem-cell-stud
y-holds-promise-kidney-disease/
 https://blog.cirm.ca.gov/2018/04/12/stem-cell-
study-holds-out-promise-for-kidney-disease/
 https://news.usc.edu/136567/usc-research-helps-
stem-cell-experts-develop-kidney-treatments-
reduce-dialysis/