OS SiA-Artificial Intelligence Digital Pathology Scanner
                     OS-SiA: Scan, Index, Analyze 
World’s First AI-Enabled Scanner
A New Generation AI-Enabled Digital Scanner That Allows To Scan, 
Index And Analyze The Tissue Slides – All At The Same Time
Usability
The AI based modules in the framework can be trained for classification problems (e.g. tumor vs benign etc.). 
User can train the module by labelling the segmented cellular objects for classification and selecting the 
features generated by the feature engineering algorithms. This trained model can be saved for analyzing 
new images to be scanned.
Advantages
• The AI scanner has custom Optra’s algorithm in the embedded AI framework with plugin architecture.
• The framework consists of core Optra’s imaging library, open source libraries like OpenCV and AI modules 
for training
• the classifiers.
• The framework defines the interfaces and provides API’s to process the images. This enables the user 
to write an
• algorithm plugin for image analysis and classification of recognized cellular objects.
• The custom algorithms provide real time ROI detection while scanning, cell quantification for IHC/HNE 
markers, rare
• event detection, morphological measurements etc. built using the core library.
• The whole slide image can be viewed in local / web based / mobility-based image viewer.
OPTRASCAN INC.,CA USA
OptraSCAN® is an ISO13485 certified company
+1 (408) 524-5300
OptraSCAN® whole slide scanners are CE marked for IVD use
[email protected] OptraSCAN® systems are for research use in North America @OptraSCAN
www.optrascan.com
OptraSCAN® is an ISO 13485 certified company
OptraSCAN® systems are CE mark for IVD use
OptraSCAN systems are for research use only in North America
Providing Accurate, Rapid and Reproducible Assessment
Nuclear Biomarker
• Identification of optical density vectors
• Computer assisted whole-slide & Regions of Interest assessment for quantification of nuclear algorithm
• Easily tunable training & classifying modules
• Generation and quantification of clinically relevant data for each case
• Batch processing and single slide analysis
Membrane Biomarker
• Highly reproducible and accurate score generation
• IHC dual-plex analysis for each biomarker analyzed
• User validation through exposed parameters opened for user interaction
• Stroke detection algorithm for filtering out residual/background staining
OptraSCAN Inc. OptraSCAN India Pvt. Ltd. 
[email protected]
100 Century Center Court, Suite 410, San Jose, Qubix SEZ, Hinjewadi Phase I
www.optrascan.com
CA 95112, USA, Tel : +1-408-524-5300 Pune, Maharashtra 020-66540900
OptraSCAN® is an ISO 13485 certified company
OptraSCAN® systems are CE mark for IVD use
OptraSCAN systems are for research use only in North America
Immuno-Oncology
• Fully automated solution for interpretation of PD-L1 IHC expression
• Score generation based on the number of PD-L1 positive cells in relation to total tumor and immune 
cells in a single read
• Computer aided region detection system based for automated evaluation of tumor nests
Prostate Cancer
• End to end, fully automated solution for prostate cancer
• ANN (artificial neural network) based classifier
• ML based histological assessment of architectural patterns
OptraSCAN Inc. OptraSCAN India Pvt. Ltd. [email protected]
100 Century Center Court, Suite 410, San Qubix SEZ, Hinjewadi Phase I www.optrascan.com
Jose, CA 95112, USA, Tel : +1-408-524-5300 Pune, Maharashtra 020-66540900