Various ways in the prevention of fatal Fever of unknown origin - Pubrica
                     VARIOUS WAYS IN  
THE PREVENTION 
OF  FATAL FEVER 
OF  UNKNOWN 
ORIGIN
An Academic presentation by
Dr. Nancy Agens, Head, Technical Operations, 
Pubrica  Group: www.pubrica.com
Email: [email protected]
Today's 
Discussion
Outline of In brief
Topics Introduction  
Personal 
Preventions  
Societal 
Preventions  Myth 
buster  Conclusion
In 
Brief
Fever is one of the most commonly seen symptoms in patients.
The diagnostic strategy of patients with Fever is well established 
 even with the Fever of unknown origin. Petersdorf and Beeson  
initially defined Fever of unknown origin (pyrexia) in 1961 as body 
 temperature higher than 38.3oC on several occasions,  
accompanied by more than three weeks of illness and failure to  
reach a diagnosis after one week of inpatient investigation.
Introductio
n
In medical service, it remains one of the most difficult diagnostic challenges.
It may arise due to many reasons, e.g., infections, inflammatory/rheumatic,malignant 
 or neoplastic invasions, and miscellaneous disorders.
It may also occur in organ transplants and immunodeficiency disorders.  
Contagious Fever is caused by bacteria, viruses or any other infection.  
Majority of the times, Fever of unknown origin is infectious by nature, followed by
neoplastic and rheumatic causes.
Contd..
Fig 1: 
Prevention  of 
fever of  
unknown 
origin
Personal 
Preventions
Make sure vaccinations are up to date. While travelling, check for additional
vaccinations if required.
Stay inside home.
Hands should be regularly washed with soap and water for atleast 20 seconds,  
especially after using the washroom, before eating, and after blowing the nose, coughing 
 or sneezing, before and after cooking, after handling animal or animal wastes.
Use alcohol-based hand sanitizer with atleast 60% alcohol, post handwash. 
 Cover oneself when someone sneezes or coughs while in proximity.
Avoid touching eyes, nose and mouth.
Contd..
Use personal protective equipment like face masks, gloves. Dispose of them 
 immediately after use.
Do not share personal items like toothbrush, comb or razor blade.
Disinfect infection-prone areas in your house like kitchen and bathroom, as they 
 harbour high concentrations of bacteria and infectious agents.
Maintain atleast 1 metre (3 feet) distance between yourself and anyone who is coughing 
 or sneezing.
Seek medical help early if you get mild symptoms like Fever, cough, difficult breathing.
Societal 
Preventions
People should be quarantined inside their home by authorities.
Schools and public offices need to close at the time of transmission. 
 Avoid face to face meetings, instead telephonic conversations.
Any Fever should be reported immediately to the nearest healthcare 
centre.
Illegal trade of wild animals and poultry products need to be banned.
People travelling from one place to another should be quarantined approximately 
 for two weeks in case of spread of unknown Fever
Myth 
buster
Antibiotics do not work against viruses, but only bacteria.
Spraying of alcohol or chlorine does not kill the infective biological agent that has 
 already entered the human body.
UV sterilization was not advisable for hand, as they cause irritation. 
 Hand dryers are not effective in killing infective agents.
In Clinical Research, older people with pre-existing medical conditions are more 
 vulnerable to contracting the illness.
Conclusion
Overall, public health laws can help in medical,control the spread of Fever of 
 unknown origin.
Preventive measures like screening, education, counselling and other 
 strategies help in minimizing the spread of Fever.
The balance between the public’s health and private rights of citizens  
transparently and ethically should be maintained to overcome the spread of 
 Fever of unknown origin.
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