Caffeine Citrate oral solution - Brown & Burk
                     Caffeine Citrate 
Oral Solution
What Caffeine Citrate 20MG/ML Solution 
for Infusion and Oral Solution Is and 
What It is Used For
Caffeine citrate 20mg/mL solution for infusion and oral solution 
contains the active substance caffeine citrate, which is a stimulant of 
the central nervous system, belonging to a group of medicines called 
methylxanthines.
Caffeine citrate 20mg/mL solution for infusion and oral solution is used in 
the treatment of interrupted breathing in premature babies (primary 
apnoea of premature newborns). These short periods when premature 
babies stop breathing are due to the baby’s breathing centres not being 
fully developed. This medicine has been shown to reduce the number of 
episodes of interrupted breathing in premature newborns. 
Warnings and Precautions
Caffeine citrate 20mg/mL solution for infusion and oral solution 
should be used with caution. Please inform your baby’s doctor:
• If your newborn suffers from seizures
• If your newborn suffers from any heart disease
• If your newborn has kidney or liver problems
• If your newborn has frequent regurgitation
• If your newborn produces more urine than usual
Possible Side Effects
Like all medicines, this medicine can cause side effects, although not everybody 
gets them. However, it is difficult to distinguish them from frequent complications 
occurring in premature babies and complications due to the disease. While under 
treatment with Caffeine citrate 20mg/mL solution for infusion and oral solution, 
your newborn may experience some of the following reactions:
• Local inflammatory reactions at the infusion site
• Cardiac disorders such as fast heart beat (tachycardia)
• Changes of sugar in blood or serum (hyperglycaemia)
• Stimulation of central nervous system such as convulsion, Cardiac 
disorders such as irregular heart beat (arrhythmia)
How To Store Caffeine Citrate 20mg/Ml 
Solution For Infusion And Oral Solution
• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiry date which is stated on 
the label.
• The expiry date refers to the last day of that month.
• The medicinal product does not require any special storage 
conditions.
• Vials of all parenteral solutions must be inspected visually for 
particulate matter prior to administration.
• After opening the vials, the medicinal product should be used 
immediately. 
About Us
Brown & Burk UK Ltd (BBUK), an 
independent generic 
pharmaceutical company founded 
in 2000, focuses on research and 
delivering quality, affordable 
healthcare globally. BBUK partners 
with top pharmaceutical 
manufacturers and healthcare 
professionals, providing 100+ 
licensed products with reliable 
supply and service across the UK.
Contact Us
+44 (0) 208 577 8200 
Micro House, 5, Marryat 
Close, Hounslow West TW4 
5DQ Middlesex, United 
Kingdom
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YOU