PEN VK S-F SOLUTION Strength 125mg-5ml and 250mg-5ml
                     PEN VK S-F 
SOLUTION 
Strength 
125mg-5ml 
and 250mg-
5ml
What Phenoxymethylpenicillin Sugar 
Free Oral Solution is and what it is 
used for
Phenoxymethylpenicillin Sugar Free Oral Solution is available in two 
strengths as a powder for reconstitution. The strength you are given will 
be decided by your doctor. Phenoxymethylpenicillin, the active ingredient, 
is an antibiotic that belongs to a group of medicines called penicillins, 
which are used to kill bacteria that cause infections in your body. Your 
medicine is used to treat bacterial infections of the ear, throat, respiratory 
tract, skin and soft tissues; prevent infections such as rheumatic fever or 
chorea recurring; and prevent pneumococcal infection (e.g. in asplenia 
and in patients with sickle cell disease).
What you need to know before you take 
Phenoxymethylpenicillin Sugar Free Oral 
Solution
Do not take Phenoxymethylpenicillin Sugar Free Oral Solution if:
• You are allergic to Phenoxymethylpenicillin or any of the other ingredients of 
this medicine
• You have ever had a bad reaction or allergic reaction to any penicillin-type 
antibiotic including cephalosporin antibiotic or other drugs
• You have ever had a skin rash or swelling of the face or neck or shortness of 
breath when taking any antibiotic
Warnings and Precautions
Talk to your doctor or pharmacist before taking 
Phenoxymethylpenicillin Sugar Free Oral Solution if
• You suffer from any stomach problems, accompanied by vomiting or diarrhoea 
- your doctor may decide that an oral antibiotic is not of benefit to you
• You suffer from any kidney problems, as you may be given a lower dose than 
normal
• You suffer from allergies and/or asthma, You suffer from allergic reactions to 
penicillin, cephalosporins or other drugs
• If you are taking the contraceptive pill. You may need to take extra 
contraceptive precaution such as using a condom 
Possible Side Effects
Hypersensitivity/Allergic reactions of all intensity levels - to the point of 
anaphylactic shock have also been observed after oral penicillin use. Severe 
anaphylactoid reactions, which occur significantly less often after oral 
administration of penicillin than after intravenous or intramuscular 
administration, may require appropriate emergency management.
• Hypersensitivity of all severities (allergic reaction) (frequency – very rare)
• Symptoms may include: difficulty breathing, muscle weakness, fever, joint 
pain, changes in blood counts, sudden swelling of the lips, cheeks, eyelids, 
tongue and throat, laryngeal oedema (accumulation of fluid in the larynx), 
bronchospasm (wheezing, shortness of breath), increase in the heartbeat, 
vasculitis (inflammation of blood vessels) and a sudden drop in blood pressure 
up to life threatening shock
• A serious skin reaction characterized by reddish non-elevated target like or 
circular patches on the trunk, often cetral blisters or mucosal lesions, skin 
peeling, ulcers of mouth, throat, genitals and eyes. These serious skin rashes 
can be preceded by fever and flu like symptoms (Toxic epidermal necrosis 
(frequnecy - rare)/Stevens –Johnsons syndrome (frequency – very rare))
• Allergic reactions including rash, itching, hives and rarely severe 
peeling/blistering of the skin (frequency - common)
• Serum sickness-like reactions (characterised by fever, chills, joint pains and 
oedema) (frequency – very rare) Seizures (frequency not known)
• pseudomembranous enterocolitis (bacterial infection of the large intestine. 
Symptoms include abdominal pain and diarrhoea)
Tell your doctor or pharmacist if you notice any of the following 
and they worry you.
Very common side effects (may affect more than 1 in 10):
• loss of appetite
Common side effects (may affect up to 1 in 10 people):
• stomach pain, pain or discomfort in the upper abdomen (gastric discomfort),  
gas (flatulence), nausea (feeling sick), vomiting (being sick), diarrhoea, 
inflamed and sore mouth (stomatitis), inflammation of the tongue (glossitis), 
rash, hives (immediate presence of hives indicates penicillin allergy, use of 
Phenoxymethylpenicillin should be discontinued), eruption of the skin 
(exanthema)
About Us
Brown & Burk UK Ltd (BBUK), an 
independent generic 
pharmaceutical company founded 
in 2000, focuses on research and 
delivering quality, affordable 
healthcare globally. BBUK partners 
with top pharmaceutical 
manufacturers and healthcare 
professionals, providing 100+ 
licensed products with reliable 
supply and service across the UK.
Contact Us
+44 (0) 208 577 8200 
Micro House, 5, Marryat Close, 
Hounslow West TW4 5DQ 
Middlesex, United Kingdom
THANK 
YOU