The human body contains a specialized system called the endocannabinoid system (ECS), which regulates various functions, including sleep, appetite, pain and immune system response. The body produces endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors in your nervous system. Studies have shown that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters. CBD Supreme is a CBD supplements specialists in Stoke-on-Trent who provides safe and natural CBD products.