post traumatic stress disorder treatment
                     NEURONS OF 
PTSD  PATIENTS 
REACT
Mental 
Health
It is no secret that some people are 
genetically  prone to PTSD. Some 
individuals are poor-tolerant  of stress 
responses. Postmortem studies show  that 
the neurons of people with PTSD are  
sensitive to glucocorticosteroids. Now 
researchers  have found a new way to 
confirm this hypothesis  by creating brain 
cells of PTSD patients from their  stem 
cells. This also helped them identify genes  
associated with glucocorticosteroid 
sensitivity.
This study also opens the door for future 
studies  and post traumatic stress disord
er treatment.
It is no secret that two people react differently 
to stress.  Therefore, two individuals may go 
through similar kinds of  circumstances, but 
one may develop PTSD, and another  not. 
Hence, it is also relatively easy to guess that 
these  individual differences have much to do 
with genetics.
However, what is challenging is to 
understand what  genetic differences 
predispose one to PTSD and make
another resilient.
In some individuals, high-stress hormone levels do 
not  cause mental health issues like PTSD. 
However, studies  from postmortem brains show 
that in those living with PTSD,  brain cells or 
neurons are more sensitive to certain types of  
stress hormones like cortisol or glucocorticoids. 
This  hypersensitivity to these hormones makes 
some people  more likely to develop signs of 
PTSD.
However, there are some limitations of studies 
done on a  dead brain. Therefore, confirming the 
hypothesis on living  brain cells is essential. 
However, there are numerous  challenges in 
studying live brain cells. After all, one cannot  
readily and safely extract cells from the brains of 
those  living with PTSD.
During the experiments, researchers found that these 
brain cells  derived from stem cells of those living 
with PTSD were more  sensitive to 
glucocorticosteroids. They could also find that this  
occurred due to the presence of specific genes 
contributing to  PTSD-dependent glucocorticoid 
response.
This study provided new insights. It demonstrated that 
stem cells of  PTSD patients could be used to 
understand the molecular  mechanism of PTSD, stress 
responses, and conduct drug screening  to find effective 
treatments.
Thank 
You