Classification of NON-ALLERGIC RHINITIS
                     Classification of  NO
N-ALLERGIC  
RHINITIS
Non-Allergic Rhinitis  
with Eosinophilia
Patients of Non-Allergic Rhinitis with 
eosinophilia  (NARE) have perennial symptoms 
with episodes of  watery discharge, itching, 
sneezing, and epiphora.
They have negative or irrelevant reports by 
skin or in  vitro allergy testing.
The specific allergy triggers are absent, but 
aggravating  factors usually include weather 
changes and exposure  to chemical irritants. 
The nasal smear shows marked  eosinophilia.
D rug-Induced  
Rhinitis
Several ANTI-HYPERTENSIVE DRUGS, such as beta-  
blockers, alpha-blockers, angiotensin-converting enzyme  
(ACE) inhibitors, and vasodilators, can result in nasal  
congestion and stuffiness.
The ANTICHOLINESTERASE DRUG (Neostigmine) used  
in myasthenia gravis have acetylcholine-like action, which  
may affect the nasal mucosa.
ASPIRIN and NSAID are well known to cause sinusitis and  
asthma.
Contraceptive pills (Estrogen) can cause nasal obstruction.
Rhinitis medicamentosa
The long-term use of topical nasal  
decongestants such as Oxymetazoline  
(Otrivin®), Xylometazoline (Nasivion®),  
etc., causes rebound congestion in the  
nose and leads to rhinitis medicamentosa. 
 It usually affects people who use these  
sprays for 7-to-10 days or longer.
Emotional rhinitis
Nose mucosa may react to several  
emotional conditions, such as anxiety,  
tension, hostility, humiliation, resentment, 
 and grief.
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