Ikgdar 100 mg
                     Ikgdar 100 mg|Rituximab 
injection |uses,dose,side 
effects,price India
Million Health Pharmaceuticals
DESCRIPTION
• Ikgdar 100mg is a anticancer medicine which prevents the 
growth and spread of cancer cells in the body. 
• Ikgdar 100mg injection also indicated for the treatment of 
Non- Hodgkins lymphoma or chronic lymphocytic and with 
combination with another anticancer drugs like methotrexate 
is used for rheumatoid arthritis symptoms in adult treatment. 
• Ikgdar 100mg with steroid regimen combination is given for 
the treatment of some rare disorders which cause blood 
vessels and other tissues inflammation in the body.
INDICATION
• Ikgdar 100mg injection and hyaluronidase human injection are 
given alone or combination with another drugs to treat certain 
types of non-Hodgkin's lymphoma and chronic lymphocytic 
leukemia (cancer start in WBC). 
• Ikgdar 100mg injection is also used with methotrexate 
(Otrexup, Rasuvo, Xatmep, others) for the treatment 
rheumatoid arthritis symptoms in adults that have been 
already treated with a some type of regimen known as tumor 
necrosis factor (TNF) inhibitor. 
Non-Hodgkin's lymphoma
PHARMACODYNAMIC
• new type of "targeted" cancer treatment and an integral part of the 
body's immune system. Naturally the body build antibodies in along 
with to an antigen which has entered the body and attach to the 
antigen for destruction by the immune system. An essential cells 
only aimed by monoclonal antibiotics, they may leads to less 
toxicity to healthy cell and it is usually treatment recommended 
only for cancers in which antigens (and the respective antibodies) 
have been already identified. Ikgdar works by linking to the CD20 
antigen on normal and malignant B-cells. Hence the body's 
essential immune security are initiated to attack and kill the marked 
B-cells. Stem cells i.eyoung cells in the bone marrow which will 
grow into the various cell types and do not have the CD20 antigen. 
After treatment,CD20 antigen allows healthy B-cells to multiply
Brand : Ikgdar
Ingredients : Rituximab 
Strength : 100mg 
Manufactured : Emcure pharmaceuticals
Package : injection
PRODUCT DETAILS
PHARMACOKINETICS
• ABSORPTION
Not available
DISTRIBUTION
Volume of distribution is 3.1 L
METABOLISM
Ikgdar 100mg metabolized by human antimurine antibody 
production.
EXCRETION
not available The half life of NHL is 22 days and for RA is 18.0 days, 
GPA and microscopic polyangitis is 23 days
DOSAGE MANAGEMENT
• Ikgdar 100mg injection is recommended to administer only 
through intravenous infusion not by IV push or bolus.
ADMINISTRATION
• Take an Ikgdar amount and diluted to final concentration of 1 
mg/ml upto 4 mg/ml as infusion (containing either 0.9% Nacl 
or 5% dextrose in water). Invert gently the bag and mix the 
solution. Dispose unused drug left in vial. 
• OVERDOSAGE: If the patients had high dose of Ikgdar 100mg
 then seek immediately to the emergency department or 
poison control help line. Please consult the doctor for further 
clarification.
DRUG INTERACTION
• Ikgdar 100mg drug interaction has limited data is available at 
present. Combination with fludarabine or cyclophosphamide 
has no effects in pharmacokinetics in CLL patients. 
Combination with methotrexate had no effects in 
pharmacokinetics.
CONTRAINDICATIONS
• Hypersensitivity or murine proteins. 
• Active severe infectons in rheumatoid arthritis Uncontrolled 
cardiac disease.
PREGNANCY
• CategoryC : animal studies reproduction shown an adverse 
effect on the fetus. 
• The drug has no sufficient and well controlled studies in 
humans, using in pregnant women benefits by warrant use of 
the drug.
LACTATION
• Ikgdar 100mg injection excreted into human milk is unknown. 
Due to the drug belongs to large protein molecule, no 
information is available. Women should not breast feed during
 Ikgdar 100mg treatment and 12 months following last dose.
STORAGE 
Store at 2°C – 3°C
Use the drug before expiry date
Protected from direct sunlight
Do not freeze or shake.
Keep away from the childerns
Discard the unused drug by asking the advice from doctor or 
pharmacist.
MISSED DOSE
• If a dose missed to take at the time then have it suddenly 
before next dose timing, if time reach for next dose, then skip 
missed dose and continue and continue the regular schedule. 
Do not have 2 dose at a same time.
CONTACT US
• EMAIL ID : [email protected]
• PHONE NO : +91-9940472902
• WEBSITE URL : https://millionpharma.com/ikgdar-100mg.php