Uploaded on Jul 24, 2019
Maball 100 mg (Rituximab) Injection
Maball 100 mg (Rituximab) Injection
Maball 100 mg (Rituximab) Injection |
uses,dosage,side effects,price india
MILLION HEALTH PHARMACEUTICALS
DESCRIPTION
Maball is a anticancer medicine which
prevents the growth and spread of cancer
cells in the body.
Maball also indicated for the treatment of
Non- Hodgkins lymphoma or chronic
lymphocytic and with combination with
another anticancer drugs like methotrexate is
used for rheumatoid arthritis symptoms in
adult treatment.
Maball with steroid regimen combination is
given for the treatment of some rare disorders
which cause blood vessels and other tissues
inflammation in the body.
INDICATION
Maball 100mg and hyaluronidase human
injection are given alone or combination with
another drugs to treat certain types of non-
Hodgkin's lymphoma and chronic lymphocytic
leukemia (cancer start in WBC).
Maball 100mg injection is also used with
methotrexate (Otrexup, Rasuvo, Xatmep,
others) for the treatment rheumatoid arthritis
symptoms in adults that have been already
treated with a some type of regimen known as
tumor necrosis factor (TNF) inhibitor.
PHARMACODYNAMIC
new type of "targeted" cancer treatment and an integral
part of the body's immune system. Naturally the body
build antibodies in along with to an antigen which has
entered the body and attach to the antigen for destruction
by the immune system. An essential cells only aimed by
monoclonal antibiotics, they may leads to less toxicity to
healthy cell and it is usually treatment recommended only
for cancers in which antigens (and the respective
antibodies) have been already identified. Maball works by
linking to the CD20 antigen on normal and malignant B-
cells. Hence the body's essential immune security are
initiated to attack and kill the marked B-cells. Stem cells
i.eyoung cells in the bone marrow which will grow into the
various cell types and do not have the CD20 antigen. After
treatment,CD20 antigen allows healthy B-cells to multiply
PRODUCT DETAILS
Brand : Maball Ingredients : Rituximab
Strength : 100mg Manufactured : Hetero Package : injection
PHARMACOKINETICS
ABSORPTION
Not available
DISTRIBUTION
volume of distribution is 3.1 L
METABOLISM
Maball 100mg metabolized by human
antimurine antibody production.
EXCRETION
not available The half life of NHL is 22 days
and for RA is 18.0 days, GPA and microscopic
polyangitis is 23 days.
DOSAGE MANAGEMENT
Maball is recommended to administer only through
intravenous infusion not by IV push or bolus.
ADMINISTRATION
Take an Maball amount and diluted to final
concentration of 1 mg/ml upto 4 mg/ml as infusion
(containing either 0.9% Nacl or 5% dextrose in
water). Invert gently the bag and mix the solution.
Dispose unused drug left in vial.
OVERDOSAGE: If the patients had high dose of
Maball then seek immediately to the emergency
department or poison control help line. Please
consult the doctor for further clarification.
PRECAUTIONS
Allgeric condition against Maball 100mg or any other
medication informs your doctor. Concerning your past
history of drug used which include in prescription,
non-prescription, vitamins &supplements, nutritional
products just inform the doctor.
While using Maball 100mg do not take any
vaccination or immunization without taking advice
from doctors. Avoid use of Maball 100mg if you are
pregnant.
It will harm the baby unborn, while using Maball
100mg use correct birth control to prevent pregnancy
and for at least 2 weeks after your treatment ends.
SIDE EFFECTS
Common effects:
fever and chills (flu like symptoms)
Less common side effects:
Weakness; nausea; headache; cough;
dyspnea; pharyngitis
DRUG INTERACTION
Maball 100mg drug interaction has limited
data is available at present. Combination with
fludarabine or cyclophosphamide has no
effects in pharmacokinetics in CLL patients.
Combination with methotrexate had no effects
in pharmacokinetics.
CONTRAINDICATIONS
Hypersensitivity or murine proteins. Active
severe infectons in rheumatoid arthritis
Uncontrolled cardiac disease.
PREGNANCY
CategoryC : animal studies reproduction
shown an adverse effect on the fetus. The
drug has no sufficient and well controlled
studies in humans, using in pregnant women
benefits by warrant use of the drug.
LACTATION
Maball 100mg excreted into human milk is
unknown. Due to the drug belongs to large
protein molecule, no information is available.
Women should not breast feed during Maball
100mg treatment and 12 months following
last dose.
STORAGE
Store at 2°C – 3°C
Use the drug before expiry date
Protected from direct sunlight
Do not freeze or shake.
Keep away from the childerns
Discard the unused drug by asking the advice
from doctor or pharmacist.
MISSED DOSE
If a dose missed to take at the time then have
it suddenly before next dose timing, if time
reach for next dose, then skip missed dose
and continue and continue the regular
schedule. Do not have 2 dose at a same time.
Contact Us:
PHONE NO +91-9940472902
EMAIL
[email protected]
WEBSITE URL https
://millionpharma.com/maball-100mg.php
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