Maball 500 mg (Rituximab) Injection
                     MABALL 500 MG 
(RITUXIMAB) 
INJECTION|USES,
DOSAGE,SIDE 
EFFECTS,PRICE INDIA
MILLION HEALTH PHARMACEUTICALS
DESCRIPTION
 Maball 500mg is a anticancer medicine which 
prevents the growth and spread of cancer cells in 
the body. 
 Maball 500mg injection also indicated for the 
treatment of Non- Hodgkins lymphoma or chronic 
lymphocytic and with combination with another 
anticancer drugs like methotrexate is used for 
rheumatoid arthritis symptoms in adult treatment. 
 Maball 500mg with steroid regimen combination is 
given for the treatment of some rare disorders 
which cause blood vessels and other tissues 
inflammation in the body.
INDICATION
 Maball 500mg injection and hyaluronidase human 
injection are given alone or combination with another 
drugs to treat certain types of non-Hodgkin's 
lymphoma and chronic lymphocytic leukemia (cancer 
start in WBC).
  Maball 500mg injection is also used with methotrexate 
(Otrexup, Rasuvo, Xatmep, others) for the treatment 
rheumatoid arthritis symptoms in adults that have 
been already treated with a some type of regimen 
known as tumor necrosis factor (TNF) inhibitor. 
 Maball 500mg is a type in a classification of drugs 
called monoclonal antibodies. 

PHARMACODYNAMIC
 new type of "targeted" cancer treatment and an integral part 
of the body's immune system. Naturally the body build 
antibodies in along with to an antigen which has entered the 
body and attach to the antigen for destruction by the 
immune system. An essential cells only aimed by monoclonal 
antibiotics, they may leads to less toxicity to healthy cell and 
it is usually treatment recommended only for cancers in 
which antigens (and the respective antibodies) have been 
already identified. Maball works by linking to the CD20 
antigen on normal and malignant B-cells. Hence the body's 
essential immune security are initiated to attack and kill the 
marked B-cells. Stem cells i.eyoung cells in the bone marrow 
which will grow into the various cell types and do not have 
the CD20 antigen. After treatment,CD20 antigen allows 
healthy B-cells to multiply
PRODUCT DETAILS
Brand : Maball
Ingredients : Rituximab 
Strength : 500mg 
Manufactured : Hetero
Package : injection
PHARMACOKINETICS
 ABSORPTION
Not available
DISTRIBUTION
volume of distribution is 3.1 L
METABOLISM
Maball 500mg metabolized by human antimurine 
antibody production.
EXCRETION
not available The half life of NHL is 22 days and for 
RA is 18.0 days, GPA and microscopic polyangitis is 23 
days
DOSAGE MANAGEMENT
 Allgeric condition against Maball 500mg injection or 
any other medication informs your doctor. Concerning 
your past history of drug used which include in 
prescription, non-prescription, vitamins &supplements, 
nutritional products just inform the doctor. 
 While using Maball 500mg do not take any vaccination 
or immunization without taking advice from doctors.
  Avoid use of Maball 500mg injection may affect the 
ability to have children in women. Inform your doctor 
if you planning to pregnant. It is unknown whether 
Maball 500mg passes into breast milk , avoid breast-
feed while on Maball 500mg injection treatment.
PRECAUTIONS
 Allgeric condition against Maball 500mg or any other 
medication informs your doctor. Concerning your past 
history of drug used which include in prescription, 
non-prescription, vitamins &supplements, nutritional 
products just inform the doctor. 
 While using Maball 500mg injection do not take any 
vaccination or immunization without taking advice 
from doctors. Avoid use of Maball 500mg if you are 
pregnant. It will harm the baby unborn, while using 
Maball 500mg use correct birth control to prevent 
pregnancy and for at least 2 weeks after your 
treatment ends.
SIDE EFFECTS
 COMMON EFFECTS 
fever and chills (flu lik symptoms)LESS 
COMMON SIDE EFFECTS
Weakness; nausea; headache; cough; 
dyspnae; pharyngitis
DRUG INTERACTION
 Maball 500mg drug interaction has limited 
data is available at present. Combination 
with fludarabine or cyclophosphamide has no 
effects in pharmacokinetics in CLL patients. 
Combination with methotrexate had no 
effects in pharmacokinetics.
CONTRAINDICATIONS
 Hypersensitivity or murine proteins. Active 
severe infectons in rheumatoid arthritis 
Uncontrolled cardiac disease.
PREGNANCY
 CategoryC : animal studies reproduction 
shown an adverse effect on the fetus. The 
drug has no sufficient and well controlled 
studies in humans, using in pregnant women 
benefits by warrant use of the drug.
LACTATION
 Maball 500mg excreted into human milk is 
unknown. Due to the drug belongs to large 
protein molecule, no information is 
available. Women should not breast feed 
during Maball 500mg injection treatment and 
12 months following last dose.
STORAGE
 Store at 2°C – 3°C
Use the drug before expiry date
Protected from direct sunlight
Do not freeze or shake.
Keep away from the childerns
Discard the unused drug by asking the advice 
from doctor or pharmacist.
MISSED DOSE
 If a dose missed to take at the time then 
have it suddenly before next dose timing, if 
time reach for next dose, then skip missed 
dose and continue and continue the regular 
schedule. Do not have 2 dose at a same time.
CONTACT US
 EMAIL ID 
[email protected]
 PHONE NO 
   +91-9940472902
 WEBSITE URL 
    https://
millionpharma.com/maball-    500mg.php