Mabtas 500mg
                     MABTAS 500MG - ANTICANCER 
DRUGS | VIEW USES, SIDE 
EFFECTS AND PRICE | MHP
MILLION HEALTH PHARMACEUTICALS
DESCRIPTION
• Mabtas 500mg is a anticancer medicine which prevents 
the growth and spread of cancer cells in the body. 
• Mabtas 500mg injection also indicated for the treatment of 
Non- Hodgkins lymphoma or chronic lymphocytic and with 
combination with another anticancer drugs like 
methotrexate is used for rheumatoid arthritis symptoms in 
adult treatment. 
• Mabtas 500mg with steroid regimen combination is given 
for the treatment of some rare disorders which cause 
blood vessels and other tissues inflammation in the body.
INDICATION
• Mabtas 500mg injection and hyaluronidase human 
injection are given alone or combination with another 
drugs to treat certain types of non-Hodgkin's lymphoma 
and chronic lymphocytic leukemia (cancer start in WBC). 
• Mabtas 500mg injection is also used with methotrexate 
(Otrexup, Rasuvo, Xatmep, others) for the treatment 
rheumatoid arthritis symptoms in adults that have been 
already treated with a some type of regimen known as 
tumor necrosis factor (TNF) inhibitor.
• Mabtas 500mg injection is a type in a classification of 
drugs called monoclonal antibodies. 
Chronic 
Lymphoma
PHARMACOKINETICS
• new type of "targeted" cancer treatment and an integral part of 
the body's immune system. Naturally the body build antibodies 
in along with to an antigen which has entered the body and 
attach to the antigen for destruction by the immune system. An 
essential cells only aimed by monoclonal antibiotics, they may 
leads to less toxicity to healthy cell and it is usually treatment 
recommended only for cancers in which antigens (and the 
respective antibodies) have been already identified. Mabtas 
works by linking to the CD20 antigen on normal and malignant 
B-cells. Hence the body's essential immune security are 
initiated to attack and kill the marked B-cells. Stem cells 
i.eyoung cells in the bone marrow which will grow into the 
various cell types and do not have the CD20 antigen. After 
treatment,CD20 antigen allows healthy B-cells to multiply
PRODUCT 
DETAILS
Brand : Mabtas
Ingredients : 
Rituximab 
Strength : 
500mg 
Manufactured : 
Intas 
pharmaceuticals
Package : 
injection
PHARMACOKINETICS
• ABSORPTION
Not available
DISTRIBUTION
volume of distribution is 3.1 L
METABOLISM
Maball 100mg metabolized by human antimurine antibody 
production.
EXCRETION
not available The half life of NHL is 22 days and for RA is 18.0 
days, GPA and microscopic polyangitis is 23 days.
DOSAGE MANAGEMENT
• Mabtas is recommended to administer only through 
intravenous infusion not by IV push or bolus.
ADMINISTRATION:
• Take an Mabtas amount and diluted to final concentration 
of 1 mg/ml upto 4 mg/ml as infusion (containing either 
0.9% Nacl or 5% dextrose in water). Invert gently the bag 
and mix the solution. Dispose unused drug left in vial. 
  OVERDOSAGE: If the patients had high dose of Mabtas 
       500mg
• then seek immediately to the emergency department or 
poison control help line. Please consult the doctor for 
further clarification.
DRUG INTERACTION
• Mabtas 500mg injection drug interaction has limited data 
is available at present. 
• Combination with fludarabine or cyclophosphamide has 
no effects in pharmacokinetics in CLL patients. 
Combination with methotrexate had no effects in 
pharmacokinetics.
CONTRAINDICATIONS
• Hypersensitivity or murine proteins. Active severe 
infectons in rheumatoid arthritis Uncontrolled cardiac 
disease.
PREGNANCY
• CategoryC : animal studies reproduction shown an 
adverse effect on the fetus. The drug has no sufficient 
and well controlled studies in humans, using in pregnant 
women benefits by warrant use of the drug.
LACTATION
• Mabtas 500mg excreted into human milk is unknown. Due 
to the drug belongs to large protein molecule, no 
information is available. Women should not breast feed 
during Mabtas 500mg injection treatment and 12 months 
following last dose.
STORAGE 
• Store at 2°C – 3°C Use the drug before expiry date 
Protected from direct sunlight Do not freeze or shake. 
Keep away from the childerns Discard the unused drug by 
asking the advice from doctor or pharmacist
MISSED DOSE
• If a dose missed to take at the time then have it suddenly 
before next dose timing, if time reach for next dose, then 
skip missed dose and continue and continue the regular 
schedule. Do not have 2 dose at a same time.
CONTACT US:
• EMAIL ID : [email protected]
• PHONE NO : +91-9940472902
• WEBSITE URL : https://millionpharma.com/mabtas-
500mg.php