Uploaded on Jul 30, 2019
Olimab 60mg injection
Olimab 60mg injection
Olimab 60mg injection
(Denosumab) - MHP
MILLION HEALTH PHARMACEUTICALS
olimab 60mg , olimab 60mg injection , olimab
60mg price in India
DESCRIPTION
Olimab 60mg is a human monoclonal
antibody for the treatment of
osteoporosis, treatment-persuaded bone
loss, metastases to bone, and giant cell
tumor of bone.
Olimab 60mg injection is contraindicated
in people with low blood calcium levels.
Olimab 60mg is prescription drug which
is used under the guidance of medical
oncologist.
INDICATION
• Olimab 60mg injection Indicated for treatment
ofosteoporosis at high risk postmenopausal
women with (end of menopause/ change of life),
whose have serious problem of fractures raised or
who failed to other medication of osteoporosis.
• Olimab 60mg Indicated for treatment of Breast
cancer in women whose taking certain treatment
which make severe their risk of fractures and
bone loss in men with prostate cancer.
• Indicated for treatment in adults and some
adolescents with giant cell tumor of bone which
cannot treat with surgery / surgery is not possible
is treated with Olimab 60mg injection.
MECHANISM OF ACTION
Denosumab (Olimab 60mg
)mechanism by aiming a protein called
RANKL, which is required for new
osteoclasts to be made and to
function. This promote to inhibit
further breakdown of bone and
reduces the risk of problems caused by
secondary bone cancer, such as
fractures. It can also promote to
decreased pain caused by secondary
bone cancer.
PRODUCT DETAILS
Brand :Olimab
Ingredients : Denosumab
Strength : 60mg
Manufactured : Intas
Pharmaceuticals
Package : 1 injection in a prefilled
syringe
Price : olimab 60mg price in India
olimab 60mg
ADME
• Peak plasma concentration:
6.75mcg/mL
• Tmax: 10days
• Without aggregation in Olimab 60mg
pharmacokinetics with duration was
noticed upon multiple dosing of 60 mg
SC administered once every 6 months.
• Pharmacokinetics of Olimab
60mg injection will not affected by the
binding antibodies formation.
• Half-life is 25.4 days.
DOSAGE MANAGEMENT
For adult :
The prescribed dose for Osteoporosis is olimab 60mg SC
(subcutaneously) once every 6 months
The prescribed dose for Androgen Deprivation induced
bone loss is olimab 60mg injection SC q6months.
The prescribed dose is Glucocorticoid induced
osteoporosis olimab 60mg SC q6months.
The prescribed dose is Aromatase inhibitor induced bone
loss olimab 60mg injection SC q6months
For pediatric :
The prescribed dose is 13 years and older and 45kg or
more for Giant Cell Tumor of bone: The recommended
dose is of 120mg Olimab 60mg tablet given SC, with
additional 120mg doses on days 8 and 15 of the 1st
month treatmentevery 4 weeks.
OVERDOSE
No experienced with Olimab
60mg injection overdose. If
occurs take the patient to
emergency department and call
poison control
PRECAUTIONS
• Before starting denosumab should be corrected.
Hypocalcemia may worsen, specifically in
patients with renal impairment. Sufficiently
supplement patients with calcium and vitamin D.
• Olimab 60mg injection has negative effects of
immuno-suppressantsmay improve. Especially
the harm for severe infections may be raised.
Discuss with your doctor of any immuno-
suppressive drugs you early consume.
• While treatment with Olimab have
Osteonecrosis of the jaw (ONJ) has been reported
with denosumab – check for symptoms.
SIDE EFFECTS
Common side effects for the
patient taking Olimab
60mg injection :
• Nausea
• Fatigue
• Muscle weakness
• Hypophosphatemia.
SIDE EFFECTS
Less common side effects for patients taking Olimab
60mg :
• Diarrhae
• Shortness of breath
• Hypocalcemia
• Joint pain
• Hypocalcemia
• Cough
• Arthralgia
• Limb pain
• Eczema
• Headache
• Eczema
• Rash
DRUG INTERACTION
No formal drug-drug interaction with
denosumab (Olimab 60mg) during trials.
When concomitant use with some
anticancer drug, orthopedic drugs, vaccines
will lead to risk of adverse effects can be
increased
CONTRAINDICATION:
Olimab 60mg injection is contraindicated in
Hypocalcemia
Pregnancy
Hypersensitivity
PREGNANCY
category C
The Olimab 60mg which has no enough data in
pregnant women to convey any drug analog risk
for adverse development outcomes the drug in
pregnant women is contraindicated for use
because it may cause serious risk to the fetus.
LACTATION:
Olimab 60mg injection is excreted into human
milk is not known. Since possible for severe side
effects occurs in nursing infants from Olimab
60mg injection. Avoid breastfeeding during
treatment of Denosumab.
STORAGE
Store at 2°C to 8°C in the original container.
Avoid freeze.
Before to administration keep at room temperature.
Olimab 60mg protect from direct light and heat.
MISSED DOSE:
If Olimab 60mg dose is missed then have the dose
immediately before next dose duration. Next dose
time reaches then left off the missed dose and
follows regular schedule. Avoid taking double dose
at same time.
Please consult the doctor for further information.
CONTACT US
PHONE NO : +91-9940472902
EMAIL ID [email protected]
WEBSITE URL
https://millionpharma.com/olimab-60mg.php
KEYWORDS
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