Reditux 500 mg Injection
                     Reditux 500 mg Injection|
Rituximab|uses,dosage,
side effects,price india
MILLION HEALTH PHAR MACEUTICALS
DESCRIPTION
Reditux 500mg is a anticancer medicine which prevents 
the growth and spread of cancer cells in the body. 
Reditux 500mg also indicated for the treatment of Non- 
Hodgkins lymphoma or chronic lymphocytic and with 
combination with another anticancer drugs like 
methotrexate is used for rheumatoid arthritis 
symptoms in adult treatment. 
Reditux 500mg injection with steroid regimen 
combination is given for the treatment of some rare 
disorders which cause blood vessels and other tissues 
inflammation in the body.
INDICATION
Reditux 500mg and hyaluronidase human injection 
are given alone or combination with another drugs to 
treat certain types of non-Hodgkin's lymphoma and 
chronic lymphocytic leukemia (cancer start in WBC). 
Reditux 500mg injection is also used with 
methotrexate (Otrexup, Rasuvo, Xatmep, others) for 
the treatment rheumatoid arthritis symptoms in 
adults that have been already treated with a some 
type of regimen known as tumor necrosis factor (TNF) 
inhibitor. 
Reditux 500mg is a type in a classification of drugs 
called monoclonal antibodies.
NON_HODGKINS 
LYMPHOMA
PHARMACODYNAMIC
new type of "targeted" cancer treatment and an integral part of 
the body's immune system. Naturally the body build antibodies in 
along with to an antigen which has entered the body and attach 
to the antigen for destruction by the immune system. An essential 
cells only aimed by monoclonal antibiotics, they may leads to less 
toxicity to healthy cell and it is usually treatment recommended 
only for cancers in which antigens (and the respective antibodies) 
have been already identified. Reditux works by linking to the 
CD20 antigen on normal and malignant B-cells. Hence the body's 
essential immune security are initiated to attack and kill the 
marked B-cells. Stem cells i.eyoung cells in the bone marrow 
which will grow into the various cell types and do not have the 
CD20 antigen. After treatment,CD20 antigen allows healthy B-
cells to multiply
PRODUCT DETAILS
Brand : Reditux
Ingredients : 
Rituximab 
Strength :500mg 
Manufactured : 
Dr.Reddy’s 
Package : 
injection
PHARMACOKINETICS
ABSORPTION
Not available
DISTRIBUTION
volume of distribution is 3.1 L
METABOLISM
Reditux 500mg injection metabolized by human antimurine 
antibody production.
EXCRETION
not available The half life of NHL is 22 days and for RA is 
18.0 days, GPA and microscopic polyangitis is 23 days.
DOSAGE MANAGEMENT
Reditux 500mg is recommended to administer only 
through intravenous infusion not by IV push or bolus.
ADMINISTRATION
Take an Reditux 500mg amount and diluted to final 
concentration of 1 mg/ml upto 4 mg/ml as infusion 
(containing either 0.9% Nacl or 5% dextrose in water). 
Invert gently the bag and mix the solution. Dispose 
unused drug left in vial. 
OVERDOSAGE: If the patients had high dose of 
Reditux then seek immediately to the emergency 
department or poison control help line. Please consult 
the doctor for further clarification.
PRECAUTIONS
Allgeric condition against Reditux 500mg injection or any 
other medication informs your doctor. Concerning your 
past history of drug used which include in prescription, 
non-prescription, vitamins &supplements, nutritional 
products just inform the doctor. 
While using Reditux 500mg do not take any vaccination or 
immunization without taking advice from doctors. Avoid 
use of Reditux 500mg if you are pregnant.
 It will harm the baby unborn, while using Reditux
 500mg injection use correct birth control to prevent 
pregnancy and for at least 2 weeks after your treatment 
ends.
SIDE EFFECTS
o COMMON EFFECTS 
fever and chills (flu lik symptoms)
LESS COMMON SIDE EFFECTS
Weakness; nausea; headache; cough; 
dyspnae; pharyngitis
DRUG INTERACTION
Reditux 500mg drug interaction has limited 
data is available at present. Combination with 
fludarabine or cyclophosphamide has no 
effects in pharmacokinetics in CLL patients. 
Combination with methotrexate had no effects 
in pharmacokinetics.
CONTRAINDICATIONS
Hypersensitivity or murine proteins. Active 
severe infectons in rheumatoid arthritis 
Uncontrolled cardiac disease.
PREGNANCY
CategoryC : animal studies reproduction 
shown an adverse effect on the fetus. The 
drug has no sufficient and well controlled 
studies in humans, using in pregnant women 
benefits by warrant use of the drug.
LACTATION
• Reditux 500mg injection excreted into human 
milk is unknown. Due to the drug belongs to 
large protein molecule, no information is 
available. Women should not breast feed 
during Reditux 500mg treatment and 12 
months following last dose.
STORAGE
 
Store at 2°C – 3°C Use the drug before expiry 
date Protected from direct sunlight Do not 
freeze or shake. Keep away from the childrens 
Discard the unused drug by asking the advice 
from doctor or pharmacist.
MISSED DOSE
If a dose missed to take at the time then have 
it suddenly before next dose timing, if time 
reach for next dose, then skip missed dose 
and continue and continue the regular 
schedule. Do not have 2 dose at a same time.
CONTACT US
EMAIL 
ID : [email protected]
PHONE NO : +91-9940472902
WEBSITE URL : 
https://millionpharma.com/reditux-500mg.php