Ayurveda is the fundamental science of medicine that covers all aspects of human life. It describes many diseases and classifies them into different categories based on their symptoms and origin. In this regard, Adibala Pravritta and Janmabala Pravritta are categorized under Garbhajanya vikriti, mainly arising from maternal or paternal problems and defects in progeny.
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Review of Ayurveda and Modern Perspectives on Congenital Anomalies or Anatomical Abnormalities
12 IX September 2024
https://doi.org/10.22214/ijraset.2024.64107
International Journal for Research in Applied Science & Engineering Technology (IJRASET)
ISSN: 2321-9653; IC Value: 45.98; SJ Impact Factor: 7.538
Volume 12 Issue IX Sep 2024- Available at www.ijraset.com
Review of Ayurveda and Modern Perspectives on
Congenital Anomalies or Anatomical Abnormalities
1 2 3
Prakarti Panwar , Mukesh Kumar , Rakesh Kumar Sharma
1, 2MD Scholar, P.G. Department of Rachana Sharir, PGIA, DSRRAU, Jodhpur, Rajasthan
3Associate Professor, P.G. Department of Rachana Sharir, PGIA, DSRRAU, Jodhpur, Rajasthan
Abstract: Ayurveda is the fundamental science of medicine that covers all aspects of human life. It describes many diseases and
classifies them into different categories based on their symptoms and origin. In this regard, Adibala Pravritta and Janmabala
Pravritta are categorized under Garbhajanya vikriti, mainly arising from maternal or paternal problems and defects in progeny.
The faulty diet and lifestyle of the mother are also considered responsible for congenital birth defects. Defects in Beeja &
Beejabhaga play an important role in the pathogenesis of such diseases. Similar to Ayurveda, modern science also mentions
structural anomalies and developmental issues like heart defects, spina bifida and club foot as common anatomical
abnormalities. Ayurveda scholars mention various factors – Matrija, Pitrija, Aatmaja, Rasaja, Satmyaja and Sattvaja – as Shad
Garbhkarabhavas that play a vital role in healthy progeny. Factors such as awful conduct, abnormalities in Shad
Garbhkarabhavas and genetic predisposition trigger the pathogenesis of Garbhajanya vikriti.
Keywords: Garbhajanya Vikriti, Matrija, Pitrija, Congenital Anomalies, Beeja, Beejabhaga.
I. INTRODUCTION
Ayurveda, an ancient system of Indian medicine, addresses many issues related to health, disease, disease treatment and disease
prevention. In this regard, Ayurveda explains several principles and guidelines for healthy offspring and the birth of a healthy child.
The six factors described as Shad Garbhkarabhavas play an important role in ensuring the health of the offspring and normal
childbirth. Avoidance or defects in the factors Matrija, Pitrija, Aatmaja, Rasaja, Satmyaja and Sattvaja may lead to birth defects or
anatomical abnormalities. Beeja-Dosha and Matrija Vikriti are considered responsible for Garbhaj Vikritiya, which may include
abnormalities in the growth and development of the fetus such as abnormal shape & size, snake & scorpion-like shapes or crooked
legs. Improper physical, mental and social behavior during pregnancy as well as environmental and genetic factors, may lead to an
unhealthy or defective childbirth. Ayurveda describes many anatomical perspectives of the body under the stream of “Sharir
Rachana,” including diseases related to anatomical abnormalities or birth defects. Anatomical abnormalities can be caused by
vitiation in Beeja & Beejabhaga.
The common manifestations of anatomical defects are as follows
1) Absence of organs
2) Structural defects in organs
3) Excess or extra development of tissue
4) Anatomical variations
5) Improper development of body parts, etc.
The other factors which can leads birth defects includes Kula or Gotra of parents, health status of mother, age of mother and father,
status of reproductive organs, dietary factors and hereditary factors etc.
A. Garbhajanya Vikriti (Congenital anomaly)
Acharya Sushruta described Nastikata and Ashubha karma of parents as causes of Garbhajanyavikriti along with Purvajanmakrita
Karma. Pathologically, vitiation of Vata and Dosha Prakopa during pregnancy mainly causes birth defects. These can lead to defects
in the fetus and the shape of the fetus becomes like Sarpa, Vrishchika and Kusmanda etc. The Garbhajanya Vikriti are responsible
for the birth of Kubja, Kuni, Pangu, Muka, and Minmin children. Anatomical abnormalities mainly occur due to defects in sperm
and ovum, inappropriate conditions of the uterus, mother's age, Dosha predominance, time and quality of conception, period of
conception, mother's food regimen, and parents' mental status, etc. Congenital abnormalities mainly occur in young women
belonging to the teenage group or in middle-aged women conceiving after 35 years.
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International Journal for Research in Applied Science & Engineering Technology (IJRASET)
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Matrija, Pitrija and Aatmaja Bhavas cannot be changed as they come from the parents and Poorvajanma Samskaras (as a result of
the code of conduct), respectively, but the other three Bhavas factors, namely, Satmyaja, Rasaja and Sattvaja Bhavas, practiced
properly can modify the intrauterine environment and psychosomatic health of the mother, producing a healthy impact on the fetus.
It is a known fact now that environmental factors can influence the genome.
Acharya Charaka has described five factors responsible for Vikriti as follows -
1) Beeja Dosha: The chromosomal abnormalities of the modern science can be correlated with Beejadosha which is responsible
for diseases like Vandhya, Vaarta and Putipraja etc. Teratologic abnormalities are determined by the condition of the "Beej"
(reproductive material), not the physical status of the pair. In other words, if any section of the "Beej" is defective, the body part
that develops from that portion of the "Beej" will be abnormal. Any biological abnormality must be accompanied by a "Beej"
abnormality. For example, if a person with Kustha (skin disorder) has a fault in the part of the "Beej" responsible for skin
creation, the child may develop Kustha. However, if that portion is normal, the child will be healthy. Similarly, a child whose
father is blind may experience the same condition. The "Beej" can be affected by a variety of dietary regimens for pregnant
women. If the entire "Beej" is harmed, the woman will not be able to conceive. However, if only a tiny section is afflicted, the
child will be born with the abnormalities of the corresponding mother body part. Bhela has also supported Charaka's viewpoint.
Chakrapani clarified words such as "Beej" and "Beej-Bhagavayava" (seed-part). "Beej-Bhagavayavas" are portions of the seed
that are involved in the development of various organs (chromosomes). He goes on to say that human sperm and ovum are
nothing more than a collection of "Beej-Bhagavayavas" (chromosomes) that correspond to each organ and result in the birth of
an individual comprised of organs unique to that species.
2) Atmakarmaja Dosha: Papakarma may affect fetus and it may acquire shape of Sarpa and Vrishchika, etc. Ayurveda has long
recognized that certain preexisting non-religious and banned activities can be the root causes of some ailments. Sushruta
demonstrated the link between congenital deformities and the previous actions of the parents and child. The fetus may develop
characteristics resembling a snake, scorpion or field pumpkin due to these previous actions. These deformities are believed to
be the result of past life sins or evil deeds. Therefore, the abnormalities in the child should be attributed to the ill acts of the
parents, the child's own past deeds or an intensified condition of the vitiated humors. Poorvjanamkrita Karma is believed to be
responsible for the fetal malformations caused by the Jeeva's past life actions.
3) Aashaya Dosha: Garbhashaya Dosha in the form of Yonivyapada; which can be correlated with the modern diseases in which
malformation of uterus occurs as unicornuate and septate uterus etc. A congenital deformity in the fetus can be caused by any
problem in the uterus. Issues in the genital organs, including amniotic fluid (specifically its abundance), can alter the
environment of the growing fetus, leading to fetal malformations. Structural or functional deformities in the uterine body, ovary
or fallopian tube can cause fetal abnormalities.
4) Kaala Dosha: Conception on 1st, 2nd or 3rd day of Rajasravakala may become responsible for Asampurn Angas and
Mritagarbha etc. Ancient Ayurvedic scholars have interpreted the word "Kaala" in various ways. It could refer to seasonal
changes such as cold, heat and rain. Kaala also denotes the age of the parents. When discussing this topic, it is important to
consider the references of Kashyapa Samhita. In this book, Kaala has been used to refer to Puhspa-Kaala (menstrual phase),
Beeja Kaala (ovulation time) and Garbhavastha Kaala (gestational period). According to ancient thinkers, women were
expected to adhere to specific standards during these three times. Failure to follow these regulations correctly could have a
negative impact on the developing fetus.
5) Matruja Ahara-Vihara Dosha: Garbhopaghatakar Aahara-Vihara like Atiamla, Atimamsa-Matsyasevana, Atinidra and
Atimadhyapana etc. may leads Garbha Vikriti like Badhira, Gadgada, Heenanga, Khalitya, Shwitra and Kushta etc. Keep in
mind that a fetus is entirely reliant on the mother for its nourishment and well-being during pregnancy. Therefore, a woman
who wants to ensure her child's healthy development should avoid consuming dangerous foods and engaging in risky activities.
This knowledge has been recognized since ancient times. Pregnant women are advised to refrain from eating beef as it is
believed that it could result in birth defects. In the Brhadaranyakopanisad, there is a description of a dietary regimen
recommended for both partners to enhance the quality of their offspring.
B. Skin Abnormalities
Hyperpigmentation, Vridhi and discoloration are common skin abnormalities. These issues can affect the outermost layer of the skin
due to genetic defects, leading to changes in complexion and texture. Genetic factors can also cause other abnormalities such as
Vyanga, Tilkalka, Ajagalika, Mashak and Kustha. When genetic factors affect different layers of the skin, various skin ailments such
as Visarpa, Kilas and Shivtra may arise.
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International Journal for Research in Applied Science & Engineering Technology (IJRASET)
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C. Reproductive Abnormalities
Dwyerita is a sexual abnormality in which a person possesses both ovarian and testicular tissue. Pavanendriya is another
abnormality that can be correlated with infertility. Other sexual abnormalities include Samskarvahi, Narashanda, Irsyabhirati and
Vakri etc. Reproductive abnormalities can also arise due to defects in the uterus, sperm, and ovum etc.
D. Metabolic Abnormalities
Sushruta described Sahaja Prameha as hereditary condition which may occurs wither from the maternal or paternal factors and
inherited from previous to next generation. The vitiation of Shukra and Shonita of parents mainly considered responsible for such
types of condition.
E. Modern Perspectives
"The defects in the ovum, sperm, uterus, time factor, changes in genes, mutations, and abnormalities in genetic materials may lead to
congenital anomalies. Mutations in gene sequences can also cause genetic abnormalities. A mutation in one gene or sequence may
lead to monogenic disorders, while mutations in multiple genes may lead to multifactorial disorders. Modern science has described
various genetic disorders, including chromosomal disorders, mitochondrial disorders and multifactorial disorders. Examples of
common anatomical abnormalities include sickle cell disease, polycystic kidney disease, cystic fibrosis, and chronic myeloid
leukemia. Many structural abnormalities have been described in which the improper formation of organs or absence of organs may
occur. Examples of such diseases include ventricular septal defect, spina bifida and cleft lip, among others. Clinically, these diseases
involve manifestations such as improper closure of the spinal cord, abnormal bladder position, gaps in the lips, abnormalities in the
heart, nodular shape of the liver, enlarged liver, absence of the portal vein valve, abnormal thinning of vessel walls, vessel
enlargement, and abnormal vascular dilatation. The two major categories of anatomical abnormalities in modern science are
structural abnormalities and developmental abnormalities. Structural anomalies include heart defects, cleft lip or palate, spina bifida,
and clubfoot, among others. Developmental issues include Down syndrome, hearing impairments, visual impairments, cerebral
palsy, and muscular dystrophy, among others."
-Down syndrome person born with an extra chromosome; which affects development of brain and body.
-Visual impairments involve irregular eye shape or improper coordination amongst the brain and eyes so visual defects arises. In
hearing impairments the ear does not work properly.
-Cerebral palsy is a condition in which motor disability occurs; it affects movement, balance and posture. The condition mainly
occurs due to the damage in brain during the development phase. Muscular dystrophy affects muscles, the muscles become weaker
with the time during the development phase.
-Muscular dystrophy affects muscles, the muscles become weaker with the time during the development phase.
II. AIMS AND OBJECTIVES
1) To study and see the relation of Shada Garbhakar Bhavas with congenital and hereditary disorders.
2) To suggest a protocol for checking such birth defects.
III. DISCUSSION
Science is the result of human curiosity. People have examined and analyzed natural processes that occur in the body through
microscopic examinations. It’s important to note that the Samhita was composed based on direct knowledge and enlightenment
using the instruments and facilities available at the time.
The embryo develops by the fusing of male and female gametes, which is a universal reality. This fact was mentioned in the ancient
Ayurvedic Samhitas. Garbha is generated by the union of Shukra-Shonita and Jeev, which grows with the help of nutrients provided
by the mother's Aahar Ras during the prenatal period. Garbha Samagri (Ritu, Kshetra, Ambu and Beej), Shadbhavas,
Garbhiniparicharya and other supplements are required for Garbha development in addition to Shukra and Shonita. According to
Acharya, these vitamins should be taken simultaneously, as any missing component can lead to complications or prevent Garbha
formation.
The qualities of "Shudha Shukra" and "Shudha Artava" have been described in length by Acharya. If Shukra and Artava possess the
attributes described by Acharyas and unite at a specific "Ritu and Kshetra," the offspring will be healthy and possess all necessary
characteristics. If Bija, BijaBhag, BijaBhagavayava, Ritu and Kshetra are distorted, the fetus will be deformed in size, shape and
behavior. All of the "Garbhaj Vikritiya" stated in Ayurvedic books has comprehensive evidence.
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International Journal for Research in Applied Science & Engineering Technology (IJRASET)
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Recent genetics studies bear a striking resemblance to ancient Ayurveda studies. All Ayurvedic literature, including the "Vrahtrayi"
and "Lagkhutrayi," demonstrate that "Beej" is the fundamental element of creation. The part of "Beej" that will be vitiated in the
microform like gene and accountable for specific organ malformation in the fetus is indicated directly by Acharya. Our Acharya
depicted modern-day monsters as "Vikritakritya," like as serpents and scorpions. Our scriptures referred to twins as "Yamala." All
that has been said in modern times seem to have already been said in our literature as their wide vision. Some embryonic
malformations produced by "Beej Dosha," as described by our Acharya are very comparable to modern fetal deformities caused by
genetic factors. Ayurvedic literature describe a deformity called "Bandhya," which shares many traits with the English term sterility.
Bandhya cannot produce offspring due to a genetic cause (Beej Dosha), just as sterility cannot produce offspring due to
oligospermy, azoospermy, or defective ovulation. All of these factors fall within the limits of what Acharya stated, that "Beej
Dosha" means any deformity related to "Beej" (may be Pumbeej or Stribeej) can cause Bandhyat.
Ayurvedic literature also use the name "Putiprijan" to describe an Acharya whose kid dies before delivery. This type of
malformation indicates that "Beej" (Sperm or Ova) is only partially capable of producing kids. The terms "Trinputik" and "Varta"
refer to a sex abnormality in which the offspring lacks all sex traits. This disorder demonstrates a genetic defect that causes
secondary sexual traits to appear. In medical science, twins are caused by the division of a zygote into two parts and the subsequent
development of a fetus by both parts of the zygote, resulting in identical twins. In Ayurvedic science, the Vata Dosha splits the "Beej
Anu" (zygote) into two, resulting in Yamala Garbha. Many prenatal malformations resembling odd shape-serpent, scorpion and
gourd-like fetus are discussed in Ayurvedic writings. The foetal malformations recorded in Ayurvedic writings include several types
of Napumska that are unable to perform sexual activity properly, as well as various types of monsters such as "Nagaudara,"
"Upvishtaka," Lina Garbha and others. The importance of Garbhaj Vikriti in modern life is the focus of this study work. All
Acharyas believe that Aadibal Pravrita Vikritiya (Hereditary) and Janmabal Pravrita Vikritiya (Hereditary) are synonymous with
genotype and phenotypic abnormalities.
IV. CONCLUSION
Ayurveda provides a lot of information about the structure of the body and anatomical abnormalities related to the human body,
which mainly arise due to genetic and congenital factors. Garbhajanya Vikriti are abnormalities that arise from maternal or paternal
defects associated with offspring. Defects in Beeja & Beejabhaga trigger the development of these types of diseases. According to
Ayurveda, factors such as Matrija, Pitrija, Rasaja, Satmyaja, Sattvaja and Aatmaja play a significant role in the healthy
development of offspring and any abnormalities or imbalances in these factors may cause Garbhajanya Vikriti. Common clinical
manifestations of congenital anomalies or anatomical abnormalities include absence of organs, structural defects in organs, excess
tissue development, anatomical variations of organs and improper tissue development. Similarly, modern science also mentions
structural anomalies and developmental issues such as heart defects, spina bifida and clubfoot.
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