Uploaded on Sep 30, 2024
Expert fertility clinic offering personalized care from a dedicated team to support your journey to parenthood with compassion and expertise.
IVF London Brochure
A message from the founder...
IVF London is built on the pillars of science and technology in reproductive
medicine. As a scientist and an entrepreneur, I am passionate about our ethos:
‘it’s all about the journey’.
Our team pride themselves in living up to this expectation. At IVF London, we
elements of holistic therapies and emotional support to aid you in this journey.
We believe very strongly in the mind and body balance which is pivotal in the
wellbeing of any individual. Our highly experienced consultants are there to
provide a very bespoke treatment plan to suit your needs. IVF London is proud
to be a fully inclusive clinic that pledges to make your dream of parenthood a
reality. It’s the place where dreams are conceived…
Mr Alpesh Doshi
Clinic Director and Consultant Embryologist
24x7 Embryo
Monitoring by Timelapse
Technology
Supported Embryology
Consultants
Mr Alpesh Doshi
Clinic Director/Consultant Embryologist
Dr Arati Rama Rao Dr Baydaa Abdulrah im
Consultant Fertility Specialist Consultant Fertility Specialist
Dr Pari jat Bha ercharjee Dr C P Lim
Consultant Gynaecologist Endometriosis Consultant
Dr Anand Saggar Dr Jonathan Katz
Consultant Clinical Geneticist Consultant Endocrinologist
e Clinic
Waiting Are a
Zen Ro om Recovery Ward
Laborato ry
IVF
IVF is one of the primary treatments o ered for couples experiencing infertility and is a more involved
procedure than IUI as it requires stimulating your ovaries to produce eggs, retrieving your eggs, having
an embryologist fertilise them with your partners sperm or donated sperm in a laboratory, followed by
close observation of any developing embryos, until the optimum time for transfer which ensures only
the best quality embryos are placed back into your uterus so that they can continue growing as with a
normal pregnancy.
WHY?
If you or your partner have been diagnosed with a genetic, anatomical or hormonal fertility problem,
you are likely to be o ered IVF treatment as which provides a greater chance of success than other
treatments.
Your consultant will advise if an IVF treatment pathway is appropriate for you, particularly if you or your
partner have been diagnosed with any of the following;
Fallopian tube damage or blockage
Ovulation disorders including premature ovarian failure
Endometriosis
Uterine broids
Impaired sperm production
Unexplained infertility
A genetic disorder
ICSI
Intracytoplasmic Sperm Injection (ICSI) was introduced as a clinical level improvement to conventional
IVF treatments. It involves carefully selecting only one single sperm of the best quality for injection
into an egg to achieve fertilisation. s procedure is done using a high precision technique called
‘micromanipulation’. e resulting embryo is then transferred back into the uterus to continue its
development as with a normal pregnancy.
WHY?
ICSI is recommended when there is severe male factor infertility, including low sperm concentration,
poor motility, blockages in the male reproductive tract or where there is a desire to get pregnant a r
having had a vasectomy. It may also be advised when the female has a very low yield of eggs during
egg retrieval so as to directly improve the chances of fertilisation by clinical intervention. Your IVF
London consultant may also recommend this enhanced procedure if a previous IVF treatment has
resulted in a low fertilisation rate of eggs.
HOW?
e woman will be required to undergo ovarian stimulation to prepare her eggs for collection as in a
traditional IVF treatment plan. e sperm from the male partner will then be processed, washed and
inspected in our laboratory to select only one sperm which will then be carefully injected into a
retrieved egg. e aim is to inject the most normal looking sperm with good progressive movement
into each mature egg. In cases of surgically retrieved sperm ICSI or PICSI may be recommended to
achieve fertilisation.
When is ICSI
required?
Genetic
Testing
PGT-A
Also known as aneuploidy screening
Used to check the number of chromosomes in an embryo. A euploid
(normal) embryo should have 23 pairs of chromosomes
Enables the selection of a chromosomally normal embryo
Next Generation Sequencing (NGS) is used for the testing of the embryos
and is one of the most technologically advanced methods of genetic
testing
PGT-A does not guarantee a chromosomally normal embryo
Who would PGT-A be
recommended for?
Women over the age of 38
Peo ple with a history of
repeated implantation
failure
People with a history of
repeated miscarriage
Genetic
Testing
PGT-M
Also known as PGD
Recommended for couples who have a history of a genetic disease in
their family
Requires a ‘work-up’ prior to embryo creation to ensure that condition
can be tested for
Karyomapping used to test for condition
Process similar to PGT-A
PGT-SR
Used in patients where there is a chromosomal structural rearrangement
PGT-SR is appropriate for people who have had a child or pregnancy with
a chromosomal rearrangement or if you or your partner are a carrier of
any one of these three primary types of rearrangements:
Reciprocal translocations
Robertsonian translocations
Inversions
Treatments for
same-sex couples
You will be o ered support from our counselling team prior
to any treatment to help you understand the emotional and
legal issues in order that you are completely comfortable and
con dent with your decision to proceed
Our laboratory team will help you nd a suitable donor from
our collaborating European, American and UK sperm donor
banks. e matching of donors can be done with your
speci c requirements
If suitable we would always start with the mildest approach to
treatment such as Intrauterine Insemination (IUI) using donor
sperm. e procedure involves placing donor sperm closer to
the egg at the time of ovulation in the hope it is fertilised.
In some cases IVF (using donor sperm) may be more appro-
priate and o ers a higher chance of pregnancy compared to
IUI. Any resulting embryos are then transferred into your
uterus to continue development as a pregnancy.
If you are in a same-sex relationship and wish one partner to
donate her eggs and the other partner to carry the pregnancy
then ‘shared motherhood’ is an option that provides both
partners the intimate experience of a shared maternal role
when starting a family.
Treatment for
Single women
Donor insemination (DI) may be recommended as an e ective treatment
for single women who desire a start a family.
We will help you get started as a sperm recipient (via donation) process
unless you already have a donor in mind. You will begin by reviewing donor
pro les which enables you to select which donor may be the best ‘ t’ for
you. IVF London only use donors in accordance with stringent HFEA criteria.
is means that donated sperm will usually be provided by men between the
ages of 18 and 41. Sperm donors will have been required to undertake a
series of health tests/screening, including HIV and hepatitis, to ensure that
they do not pass on any serious diseases or medical conditions to you or
your baby
Sperm Donation and the Law:
Sperm donor is only able to create 10 families within the UK. e donors
identifying information must be given to the HFEA for its con dential
register. When a donor-conceived person becomes 18, they are able to
contact the HFEA and request the identifying information for their sperm
donor
Timelapse
Imaging
ere is a growing body of evidence time-lapse systems have a signi cant positive impact
on success rates compared to traditional incubators. ey generate images of the
embryos every 10 to 15 minutes, creating a time-lapse video of embryo development.
is enables our embryologists to analyse and identify any potential aberrations in
embryo development that would be missed when using conventional incubation
techniques. is helps us improve embryo selection for transfer, cryopreservation and
biopsy.
Uninterrupted culture of embryos
ensuring stable environment
Allows embryologists to analyse
every stage of embryo development
Provides ‘real-time’ footage of
embryos and a continuous overview
Allows observation of key events to
aid embryo selection for transfer
Embryoscope works hand in hand
with arti cial intelligent technology
to give embryos a quality score
Embryo Assist
AI
IVF London has partnered with Fairtility™ to introduce arti cial intelligence into the
laboratory. Embryo Assist AI powered by CHLOE™ (Cultivating Human Life through
Optimal Embryos) is a transparent AI-based decision support tool. Embryo Assist AI
provides clinicians and patients with visibility into the clinical and laboratory data to help
improve IVF outcomes.
Patients are able to watch a live feed of their embryos on their phones. e embryologists
can then interpret these images for the patients when they receive their embryo updates.
e algorithm that powers the AI has been trained on tens of thousands of embryos.
e AI starts scoring embryos from day 2 a er fertilisation and provides a running score
until blastocyst development. Along with the score, the embryos are also ranked to give
embryologists more information on which embryo to select for transfer.
Treatment
Add-Ons
Embryoscop e
Allows uninterrupted culture of embryo s
Image taken of embryo every 10-15 mins creating
time-lapse vide o
Enables embryologists to analyse every stage of
developme nt
Calcium Ionophore
Used following ICSI to aid egg activation
Indicated in patients that have had previous low
or failed fertilisation
Can also be used to aid be er blastocyst
development
is a device, also called a chip, which
can be used in the IVF laboratory to prepare and select sperm for
insemination by intracytoplasmic sperm injection (ICSI)
relies on the sperm actively
swimming through the membrane lter in the chip,
demonstrating motility
PICSI
Physiological intracytoplasmic sperm injection
Involves placing sperm with hyaluronic acid (HA)
Sperm that bind to HA are selected for injection
Helps to select mature sperm with be er DNA
Treatment
Add-Ons
EmbryoGlue®
Embryo culture media enriched with hyaluronan
Hyaluronan acts like a bridge between the embryo
and the womb
Helps the embryo and womb stick together while
reducing how much the embryo can move around
Endometrial Scratch
Lining of uterus gently scratched using thin
catheter
Localised ‘injury’ can cause uterus to start
‘repair reaction’
May increase chances of embryo implantation
Endometrial Testing (ERA, EMMA, ALICE)
Biopsy taken from uterus at time of mock embryo
transfer
Cells assessed to determine window of implantation
(ERA) Results will determine timings for subsequent
embryo transfers. EMMA and ALICE tests focus on
the microbiology of the endometrium
Intralipid Infusion
Raised natural killer cell activity can act against
embryo implantation
Intralipid infusions can help to lower the activity
of natural killer cells
Can also be used in cases of repeated miscarriage/
implantation failure
Initial consultation Treatment
Investigations
Nurse consultation Pathways
Ovarian stimulation Tablets/hormones given to aid follicle growth Ovarian stimulation Ovarian stimulation Implications counselling Implications counselling
Surrogate identi ed
Egg collection Sperm prepared in lab Egg collection and Egg collection and sperm preparation sperm preparation Donor egg selection
Meeting with lawyer
Eggs frozen Sperm sample inserted Fertilisation with Fertilisation with Recipient started on egg directly into uterus IVF/ICSI IVF/ICSI recipient cycle Commissioning couple
screened
Eggs frozen for future
use can be stored for up Embryo culture Embryo culture Donor eggs thawed Ovarian stimulation
to 55 years with consent
being renewed every 10 Egg collection and
years Embryo transfer and/or Day 5/6 embryos have
embryo freezing 5-7 cells biopsied Sperm prepared in lab
sperm preparation
Fertilisation with
IVF/ICSI
Embryos frozen while Fertilisation with
waiting for results IVF/ICSI Embryo culture and
freezing
Cells sent to genetics lab 3-month embryo
for testing (~ 2 weeks) Embryo culture quarantine
Commissioning couple
Normal/una cted Embryo transfer and/or rescreened
embryo transferred embryo freezing
Surrogate prepared for
frozen embryo transfer
Embryo transferred into
surrogate
Egg Freezing Intrauterine IVF/ICSI with Insemination IVF/ICSI Donor Eggs SurrogacyPGT
Initial consultation LGBTQ+ Treatment
Investigations
Pathways
Nurse consultation
Implications counselling Implications counselling Implications counselling Implications counselling Implications counselling Implications counselling
Donor sperm selection Surrogate identi ed
Donor sperm selection Donor sperm selection Ovarian stimulation Semen production
Partner 1 screened as Meeting with lawyer
Tablets/hormones given donor
to aid follicle growth Ovarian stimulation Egg collection Sperm freezingOvarian stimulation for Commissioning couple
partner 1 screened as donors
Sperm prepared in lab Egg collection and sperm preparation Egg collection and Egg freezing Egg donor chosendonor sperm Sperm frozen for future
preparation use can be stored for up Eggs thawed and sperm
Sperm sample inserted Fertilisation with to 55 years with consent prepared
directly into uterus IVF/ICSI Fertilisation with being renewed every 10
IVF/ICSI years. Fertilisation with ICSI
Eggs frozen for future (eggs can be split
Embryo culture and between male partners
Embryo culture use can be stored for upfreezing Please note that spermto 55 years with consent can only be frozen if Embryo culture and freezing
Partner 2 prepared for being renewed every 10 hormone replacement
Embryo transfer and/or frozen embryo transfer years therapy has not 3-month embryo
embryo freezing commenced. quarantine
Embryo thawed and
transferred Commissioning couple rescreened
Surrogate prepared for
frozen embryo transfer
Embryo transferred into
surrogate
Intrauterine IVF/ICSI with Shared Insemination with donor sperm Motherhood
Female-to-Male Male-to-Female Same-sex Male
donor sperm (ROPA) Transition Transition Surrogacy
2022 Statistics
2021 Statistics
Price List 2024
Consultations
Initial Consultation (required for all treatments. All other consultations below include the £200 £200
charge for the initial consultation)
Shared motherhood initial consultation £400
Initial Consultation including Pelvic Scan, AMH Test and Semen Analysis £565
Female Fertility Ultrasound and Diagnostic Tests
Fertility Wellness Check £480
Includes: Ultrasound scan, AMH blood test & 30 minutes consultation
HyCoSy £450
Male Fertility Assessment and Diagnostic Tests
Semen Analysis £150
Sperm DNA Fragmentation £423
Comprehensive Semen Assessment package £599
Treatment Packages
Intrauterine Insemination (IUI) £1,100
Stimulated IVF £3,700
Embryo Freezing Cycle £4,400
Required additions: HFEA fee, monitoring blood tests, culture and medication
Frozen Embryo Transfer (FET) £2450
Egg Freezing Cycle £3,400
Multicycle Packages
Duo-Stim with ICSI £9,200
2 Egg Freezing Cycles £5,950
3 Egg Freezing Cycles £8,540
2 Embryo Freezing Cycles £8,300
3 Embryo Freezing Cycles £11,995
Genetic Testing of Embryos (PGT)
PGS Next Generation Sequencing (now called PGT-A)
Analysis of up to 4 embryos, includes biopsy fee £2,950
PGT-SR (Robertsonian and Reciprocal Translocations)
Analysis of up to 8 embryos, includes biopsy fee £4,250
PGD with Karyomapping £4,950
Embryology and Other Procedures
Embryoscope + Add CHLOE - AI £750
Intracytoplasmic Sperm Injection (ICSI) + Add PICSI £200* £1,350
Zymot Micro uidic Sperm Selection £250
Extended Culture £500
Embryo Glue £250
Calcium Ionophore £495
Embryo Freezing – includes rst year of storage £935
Annual Storage Fee £300
Non-Invasive Prenatal Testing – includes pregnancy scan and photo £595
only chromosomes 13, 18, 21 and sex chromosome abnormalities
Endometrium Testing
Endometrium Receptivity Array (ERA) £1,500
Analysis of Infectios Chronic Endometritis (ALICE) £750
Endometrial Microbiome Metagenomic Analysis (EMMA) – includes ALICE £950
Endome TRIO (ERA, ALICE and EMMA) £1,742
Elstree Site: Central London Satellite:
IVF London Basinghall Clinic
Caspian House Cromwell Hospital
4 Basinghall Street
Elstree Road, EC2V 5BQ
Borehamwood
WD6 3BS Tel: 020 724 4886
ivf_londonuk
IVFLondonUK
IVF_londonUK
+44 7916 027989
020 8075 8881 / 020 8207 4115
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