Uploaded on Mar 14, 2025
Definition: Immunotherapy uses the body’s immune system to fight cancer. ● It harnesses or enhances the immune system’s natural ability to detect and destroy cancer cells. ● A variety of immunotherapies exist, including Car T Cell Therapy
What is T Cell Therapy for Cancer Immunotherapy _
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What is T Cell Therapy for
Cancer Immunotherapy ?
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TablTea obfle C oofn Cteonnttsents
1. What is Immunotherapy? 5. Mechanism of T Cell Therapy
2. What are T Cells? 6. Benefits of T Cell Therapy
3. What is T Cell Therapy for Cancer? 7. Risk Of T Cell Therapy
4. Types of T Cell Therapies 8. Conclusion
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y
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What Is
immunotherapy?
● Definition: Immunotherapy uses the body’s immune
system to fight cancer.
● It harnesses or enhances the immune system’s natural
ability to detect and destroy cancer cells.
● A variety of immunotherapies exist, including Car T Cell
Therapy.
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t-cell-therapy
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What are T
Cell ?
● T Cells are a type of white blood cell
(lymphocyte) that play a central role in the
immune system.
● There are different types of T cells:
○ Helper T Cells: Activate other immune
cells.
○ Cytotoxic T Cells: Directly kill infected or
cancerous cells.
● T cells recognize foreign invaders (like cancer
cells) through receptors on their surface.
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/car-t-cell-therapy
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● T Cell Therapy (or Adoptive Cell Therapy)
What is T Cell involves extracting T cells from a patient’s body, modifying or expanding them, and then
Therapy for reintroducing them into the patient.● The goal: To enhance the immune system's
cancer ability to recognize and destroy cancer cells.
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Types of T Cell
Therapy
● CAR-T Cell Therapy (Chimeric Antigen Receptor T-
Cell Therapy)
○ T cells are genetically engineered to express
a receptor specific to cancer cells.
● TCR-T Cell Therapy (T-Cell Receptor Therapy)
○ T cells are modified to target cancer-specific
antigens presented on the surface of tumor
cells.
● Tumor-Infiltrating Lymphocytes (TILs)
○ T cells are isolated from a patient’s tumor,
expanded in the lab, and infused back to
target the tumor.
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Mechanism of T
Cell Therapy
1. Extraction: T cells are collected from
the patient's blood or tumor tissue.
2. Modification: The T cells are
genetically modified or expanded in
the lab.
3. Reinfusion: Modified T cells are
reinfused back into the patient's body
to attack cancer cells.
4. Activation: Modified T cells seek out
and destroy tumor cells by recognizing
cancer-specific antigens.
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Benefits of LoremIpsum
Text
T Cell Lorem Lorem
Therapy Ipsum IpsumText Text
● Personalized Treatment: Uses the
patient's own immune system. TITLE
● Targeted: Specifically targets cancer
cells while sparing healthy tissues. HERE
● Long-lasting Effects: Potential for
durable responses and long-term Lorem Lorem
remission. Ipsum Ipsum
● FDA Approvals: CAR-T therapies Text Text
have been approved for certain blood
cancers. Lorem
Ipsum
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ancer/car-t-cell-therapy
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Risk Of T
Cell Therapy
Allergic reactions during the infusion.
Abnormal levels of minerals in the
blood, such as low potassium, sodium,
or phosphorous levels. A weakened
immune system, with an increased risk
of serious infections. Low blood cell
counts, which can increase the risk of
infections, fatigue, and bruising or
bleeding.
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Conclusion
T-cell therapy for cancer immunotherapy involves modifying a patient’s T cells to enhance
their ability to recognize and attack cancer cells. This approach includes methods like CAR-T
cell therapy, where T cells are engineered to target specific cancer markers. It holds promise
as a powerful treatment option, especially for certain blood cancers, by harnessing the
body’s immune system to fight cancer more effectively.
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