Uploaded on Mar 18, 2021
Pediatricians have reported the first known case of a woman, who was given the first dose of the COVID-19 vaccine during her pregnancy, giving birth to a baby with antibodies against the novel coronavirus. According to the yet-to-be peer-reviewed study, posted in the preprint server medRxiv, the mother had received a single dose of the Moderna mRNA vaccine at 36 weeks and three days of her gestation period.
Woman gives birth to first known baby with antibodies against coronavirus
Woman gives birth to first known baby with
antibodies against coronavirus, doctors say
Pediatricians have reported the first known case of a woman, who was given the first
dose of the COVID-19 vaccine during her pregnancy, giving birth to a baby with
antibodies against the novel coronavirus.
According to the yet-to-be peer-reviewed study, posted in the preprint server medRxiv,
the mother had received a single dose of the Moderna mRNA vaccine at 36 weeks and
three days of her gestation period.
Three weeks later, she gave birth to a vigorous, healthy, full-term girl, whose blood
sample taken immediately after birth revealed the presence of antibodies against the
SARS-CoV-2 virus, the study noted.
"Here, we report the first known case of an infant with SARS-CoV-2 IgG antibodies
detectable in cord blood after maternal vaccination," noted the co-authors, Paul Gilbert
and Chad Rudnick from Florida Atlantic University in the US.
The woman, who has been breastfeeding the baby exclusively, received the second dose
of the vaccine as per the normal 28-day vaccination protocol timeline, the doctors noted.
While earlier studies showed that the passage of antibodies from COVID-recovered
mothers to their foetuses via the placenta was lower than expected, the current research
suggests "potential for protection and infection risk reduction from SARS-CoV-2 with
maternal vaccination."
However, Gilber and Rudnick note that further long-term studies are needed to quantify
the antibody response in babies born to vaccinated mothers.
"Protective efficacy in newborns and ideal timing of maternal vaccination remains
unknown," the pediatricians wrote in the study.
"We urge other investigators to create pregnancy and breastfeeding registries as well as
conduct efficacy and safety studies of the COVID-19 vaccines in pregnant and
breastfeeding woman and their offspring," they added.
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