Yes, you can absolutely combine a South Africa safari and a Rwanda gorilla trekking experience into one spectacular African adventure. Joining the ultimate big-game safari in South Africa with Rwanda's misty rainforests creates a bucket-list itinerary that showcases the very best of Southern and East Africa. While South Africa delivers world-class savanna game viewing and vibrant city life, Rwanda offers an intimate encounter with the endangered mountain gorillas. Together, they form an unmatched contrast of landscapes, wildlife, and cultures.