Uploaded on Aug 11, 2023
New Super-Resolution Imaging Technology for Biomedical Research
New Super-Resolution Imaging Technology for Biomedical Research
New Super-Resolution Imaging Technology for Biomedical Research
CD BioSciences, a US-based biotechnology company focusing on the development of
imaging technology, introduced its new services based on super-resolution imaging
technology to help researchers study various cellular activities in cellular structures,
such as DNA/RNA and protein interactions, DNA replication and transcription, vesicle
motility, and bacterial transcription.
Microscopes are the most common research tools used in biological research.
Researchers typically use electron microscopes to study subcellular structures or
optical microscopes to investigate whole living cells. However, traditional
microscopes have limited resolution. For example, when the distance between two
or more fluorophores is within a few hundred nanometers, the images become
blurred. In addition, traditional microscopes cannot directly observe cellular
structures and biomolecular interactions because biological structures such as
protein complexes, the Golgi apparatus, and the cytoskeleton are below the
diffraction limit of traditional microscopes.
CD BioSciences has solved this problem with super-resolution imaging technology,
which enables scientists to directly observe cell structures and biomolecular
interactions, and study various cell activities in cell structure, such as DNA/RNA and
protein interaction, DNA replication and transcription, vesicle movement and
bacterial transcription. It has a number of advantages over traditional light
microscopy, including high resolution, the ability to study protein structure at the
organelle level, and the ability to follow the movement of individual molecules in
cells in real time. These advantages make super-resolution imaging technology a
valuable tool for researchers studying the mechanisms of cell physiology.
Furthermore, super-resolution microscopy breaks the resolution barrier while
maintaining the minimally invasive nature of optical microscopy. It enables the
observation of fine structures and molecular activities in the 10-100 nanometer
resolution range by providing 20 times the imaging resolution of optical microscopy.
It works by effectively reducing the point spread function or ensuring that the
fluorophores of a sample are not too close together to prevent blurring.
Stimulated emission depletion microscopy (STED), structured illumination
microscopy (SIM), stochastic optical reconstruction microscopy (STORM), and
two-photon excitation microscopy (TPE) are the most commonly
super-resolution microussceodpy techniques. These techniques produce super-resolution
images in the low nanometer range, allowing observation of intracellular molecular
interactions and fine cellular structures.
CD BioSciences specializes in the development and application of super-resolution
imaging technology. It offers a wide range of services including image analysis and
consulting. For more information about the new super-resolution imaging technology,
please visit
https://www.bioimagingtech.com/super-resolution-imaging-technology.html.
About CD BioSciences
CD BioSciences is a biotechnology company committed to the development of
imaging technology for many years. Its scientists can utilize high-content imaging,
nanoparticle imaging, imaging flow cytometry, time-lapse imaging, and other
techniques to image cell structure, cell migration, cell proliferation, pathogen
infection mechanisms, and interactions between protein molecules.
Comments