Aspadol is an opioid analgesic, meaning it works as a narcotic without making a person high. Aspadol works directly in the central nervous system, helping alleviate surgery pain effectively. If a person has mild pain, such as a sprain, over-the-counter drugs can easily lessen the pain. However, in case of major injuries or surgery, over-the-counter medications offer little to no help. Aspadol 100mg is highly effective in providing effective relief from pain by altering how your brain reacts to the pain signals.