Uploaded on Jul 20, 2020
Peripheral T-Cell Lymphoma (PTCL): Overview, Epidemiology, Treatment Market, Emerging Drugs and Key players
Peripheral T-Cell Lymphoma
Peripheral T-Cell Lymphoma (PTCL): Overview, Epidemiology, Treatment Market,
Emerging Drugs and Key players
Peripheral T-Cell Lymphoma (PTCL) is a diverse group of aggressive lymphomas that develop
from mature T-cells and natural killer (NK) cells.
How has Peripheral T-Cell Lymphoma impacted people's lives?
PTCL accounts for 10–15% of all non-Hodgkin lymphomas worldwide
The total incident population of Peripheral T-Cell Lymphoma (PTCL) in 7MM was
16,298 in 2017
The incident population of PTCL in the United States was 6,110; whereas in Germany,
it was 1,183 and in the UK, the number was 1,100 in 2017
PTCL accounts for 7–15% of NHLs in the United States and EU-5 countries
PTCL accounts for around 20–25% of NHLs in Japan
EU5 countries occupied around 28.48% of the patient pool amongst 7MM in 2017
How will Disease transform PTCL Market?
The current standard of care for initial PTCL market treatment is multi-agent chemotherapy.
The treatment has not significantly changed in decades and is too often unsuccessful in leading
the long-term remissions, underscoring the need for new treatments. The progress will be made
incrementally in the different subtypes.
With the new insights into the understanding of the PTCL, future endeavours for PTCL
treatment should focus on developing trials specific for different subtypes, and exploring novel
combination therapies in the front-line setting.
Apart from these approved and off-label therapies, various emerging therapies are being
evaluated in clinical trials for the treatment of PTCL and its subtypes.
Which biotechnical companies are developing Peripheral T-Cell Lymphoma drugs?
There a slew of biotechnological companies that are developing PTCL emerging therapies,
which include Azacitidine (Celgene Corporation), Denileukin diftitox (Eisai), HBI-8000 (HUYA
Bioscience International/Quintiles), COPIKTRA (Verastem), Tislelizumab (BeiGene), Keytruda
(Merck), STI-3031/IMC-001 (Sorrento Therapeutics), SP-02 (Solasia Pharma), Tipifarnib (Kura
Oncology), ALRN-6924 (Aileron Therapeutics), Ruxolitinib (Incyte), and Romidepsin +
Azacitidine and many others.
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