Muscular Dystrophy: Can Stem Cell Treatment Help?
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Muscular Dystrophy (MD) is a genetic condition that causes the muscles in your 
body to weaken and degenerate over time. There are several types of Muscular 
Dystrophies that can occur, like Becker’s Muscular Dystrophy, Limb-Girdle Muscular 
Dystrophy, etc. Of these, Duchenne Muscular Dystrophy (DMD) is known to be the 
most fatal one. However, researchers are exploring novel techniques like stem cell 
treatment to alter the genetic mutations causing the illness and improve the 
patient’s quality of life.
What Are The Signs of DMD?
The muscle weakness caused by this condition starts manifesting during early 
childhood days. Delay in achieving developmental milestones like sitting, walking, 
and even talking are signs that the child could be suffering from DMD. The 
condition usually starts with a loss of strength and function in the pelvis and thigh 
region, followed by the arms. The child has trouble standing up as a toddler and 
loses mobility by the time they are teenagers. Increased convex curvature of the 
spine and change in gait are also noticeable signs of DMD. Even the heart and lung 
functions are affected due to the weakening of the muscles in the region, causing 
breathing and other issues for the child as they grow older. This leads to a 
respiratory or cardiac failure by the time the patient reaches their twenties.
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Future of DMD Treatment With Stem Cells
Although there is no cure for DMD at present, the advancement in medicines, gene 
therapy, stem cell treatments, etc., are providing greater hope for patients to live 
longer and feel better.
Ongoing research indicates that 
mesenchymal stem cells (MSC) can help 
relieve the DMD symptoms by aiding 
muscle cell regeneration and repairing 
damaged muscle cells. Since umbilical 
cord stem cells are at an early 
development stage, they can take the 
form of any cell. Therefore, using 
Umbilical Cord Mesenchymal Stem Cells 
(UCMSCs) increases the muscle cells’ 
functionality and replenishes the stem 
pool.
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In a study conducted on mice by a team of Harvard Stem Cell Institute 
researchers, the outcome looks promising. The researchers transplanted 
healthy stem cells into the muscles of mice with muscular dystrophy and 
observed that these new cells improved the damaged muscles’ functions and 
made them contract. They also noticed that the healthy stem cells replenished 
the diseased stem cell pool, which 
could repair any damage to the muscles during future injuries.
This study further demonstrates the potential of 
stem cell therapy in treating patients with muscular degeneration caused by 
DMD or other types of muscular dystrophy. The banking of stem cells can prove 
to be a blessing for your family as well as the field of medical science.
Save your baby’s cord blood to protect them against 80+ disorders.  Call Cordlife at Toll Free No.: 1800 121 6200 | Hotline: 
+91 983016 6200 
Source: https://www.cordlifeindia.com/blog/muscular-dystrophy-can-stem-cell-treatment-help/
Save your baby’s cord blood to protect them against 80+ disorders.  Call Cordlife at Toll Free No.: 1800 121 6200 | Hotline: 
+91 983016 6200