Long-Term Neural Recording_ Advancements by Spike Neuro
                     Long-Term Neural Recording: 
Advancements by Spike Neuro
In the realm of neuroscience, long-term neural recording has emerged as a vital tool for understanding the 
intricacies of the brain. With the increasing demand for innovative solutions in neural interface technology, Spike 
Neuro stands at the forefront, offering cutting-edge neural probes designed for both acute and chronic 
applications. This blog post explores the significance of long-term neural recording and how Spike Neuro’s 
advanced products are transforming this field.
Understanding Long-Term Neural Recording
Long-term neural recording involves the continuous monitoring of electrical activity in the brain over extended 
periods. This technique is essential for various research areas, including:
1. Neurodegenerative Diseases: Long-term recordings provide insights into the progression of diseases such 
as Alzheimer's and Parkinson's, allowing researchers to observe changes in neural activity as the disease 
advances.
2. Brain-Computer Interfaces (BCIs): BCIs rely on stable and long-lasting neural recordings to translate 
brain activity into actionable commands, significantly benefiting individuals with mobility impairments.
3. Basic Neuroscience Research: Understanding the fundamental workings of the brain requires observing 
neural circuits and their functions over time, making long-term recordings crucial for research.

The Challenge of Long-Term Neural Recording
While the potential of long-term neural recording is vast, it is not without challenges. Traditional methods often 
suffer from issues such as:
● Signal Degradation: Over time, the quality of recorded signals can diminish due to electrode materials or 
biological responses.
● Inflammatory Responses: The introduction of foreign materials into the brain can provoke immune 
responses, leading to chronic inflammation and affecting signal quality.
● Data Management: Collecting and storing large volumes of data over extended periods poses logistical 
challenges, necessitating robust data management systems.
Spike Neuro’s Innovative Solutions
Spike Neuro is dedicated to overcoming these challenges with its innovative product line, particularly the 
Rubide™ series of neural probes. These probes are specifically designed to enhance the reliability and 
effectiveness of long-term neural recording.
1. Rubide™ Acute Probes
These probes are ideal for short-term studies that require high-resolution data collection. They are constructed from 
advanced materials that ensure biocompatibility and durability, minimizing inflammatory responses and ensuring clearer 
signal acquisition. The acute probes are particularly useful for initial assessments before transitioning to chronic studies.
2. Rubide™ Chronic Probes
For researchers needing extended monitoring capabilities, the Rubide™ chronic probes offer unparalleled performance. 
These probes are engineered with specialized materials that reduce tissue response and enhance biocompatibility. This 
design allows for consistent and reliable recordings over extended periods, making them perfect for long-term studies of 
neurodegenerative diseases or chronic conditions.
3. Rodent EEG/ECoG Arrays
Spike Neuro also provides rodent EEG/ECoG arrays, which are essential for capturing brain activity from multiple sites 
simultaneously. These arrays are particularly useful in preclinical studies, allowing researchers to monitor how various 
brain regions communicate over time. This comprehensive approach enhances the understanding of neural dynamics and 
can aid in developing therapies for human applications.
Collaborating for Success
At Spike Neuro, collaboration with researchers and institutions is a cornerstone of their mission. By working 
closely with clients, they can refine their products to meet the unique demands of various studies. This partnership 
approach not only enhances the design of neural probes but also facilitates knowledge sharing, leading to 
advancements in the field of neuroscience.
The Future of Long-Term Neural Recording
As the field of neuroscience continues to evolve, the need for reliable long-term neural recording solutions will 
grow. Spike Neuro’s ongoing research and development efforts aim to push the boundaries of what is possible in 
neural interfacing technology. By continually enhancing their products, Spike Neuro is set to play a pivotal role in 
advancing our understanding of the brain and its functions.
Conclusion
Long-term neural recording is a critical area of research with vast implications for neuroscience, neuroengineering, 
and clinical applications. With the innovative solutions provided by Spike Neuro, researchers now have access to 
state-of-the-art tools that significantly enhance the quality and reliability of long-term recordings. As neuroscience 
progresses, Spike Neuro will undoubtedly remain at the forefront, driving advancements that will shape the future 
of brain research and treatment.
Contact Us
Mail 
[email protected] / [email protected]
Phone
(734) 234-3076
Address
330 East Liberty Street
Lower Level
Ann Arbor, MI 48104