New Antimicrobial Susceptibility Testing Services
                     New Antimicrobial Susceptibility Testing Services
As an expert in providing solutions to assist virology and microbiology research,  
Creative Diagnostics announced the launch of its new Antimicrobial Susceptibility  
Testing (AST) services. These services are designed to help biotechnology and  
pharmaceutical researchers detect the sensitivity of test bacteria to antimicrobial  
drugs.
Antimicrobial susceptibility testing is a laboratory procedure that is primarily used to  
determine whether antimicrobial drugs have an inhibitory effect on pathogenic  
microorganisms in vitro. It can also be applied to clinically guide therapeutic drug  
selection and to understand changes in drug resistance of common pathogens in the  
region. Knowing the antibiotics to which bacteria are susceptible can shift the choice  
of antibiotics from empiric to targeted therapy.
Methods for testing drug susceptibility are based on exposing bacteria to antibiotics  
and observing their response ("phenotypic testing") or specific genetic testing  
("genetic testing"). Currently, the major methods used in clinical microbiology  
laboratories for drug susceptibility testing include paper diffusion, dilution methods  
(including agar and broth dilution), antibiotic concentration gradient quantification,  
and automated instrumentation.
Creative Diagnostics now offers Antimicrobial Susceptibility Testing services to help  
researchers determine which specific antibiotics a particular bacteria or fungus is  
sensitive to. These new AST services provide guidance on antibiotic treatment  
options and can be integrated into GLP and GMP environments with full traceability.  
Creative Diagnostics' experts can provide rapid, objective interpretation of results,  
and its active/proactive product line development ensures optimal drug-microbe  
combinations.
Creative Diagnostics' AST services include Phenotypic and Genetic methods. The  
Phenotypic method test is based on bacterial exposure to antibiotics. The most  
commonly used test is the paper susceptibility test. A drug-sensitive paper is a filter  
paper containing a certain amount of antimicrobial drug. Then, using the paper  
diffusion method, the drug-sensitive paper is placed on the surface of agar  
inoculated with the test bacteria. The drug in the filter paper diffuses through the  
agar and the concentration of antimicrobial drug decreases logarithmically as the  
diffusion distance increases.
Genetic testing detects the presence of antibiotic resistance genes in the bacterial  
genome using methods such as polymerase chain reaction, DNA chip and  loop-
mediated isothermal amplification. These assays have the advantage of being  direct 
and rapid compared to phenotypic methods. Meanwhile, Creative Diagnostics  can 
handle a wide range of types, including Aminoglycoside, Beta-Lactam,
Cephalosporin, Macrolide, Penicillin, Quinolone, and Tetracycline.
Creative Diagnostics combines infectious disease and analytical expertise to provide  
customers with the most robust portfolio of antiviral and antibacterial in vitro testing  
services. With the growing demand for new antiviral and antibacterial compounds to  
treat infectious diseases, Creative Diagnostics can also help clients test compounds in  
vitro to determine their potential efficacy in in vivo models.
For more information about Creative Diagnostics and its new Antimicrobial  
Susceptibility Testing services, please visit
https://antiviral.creative-diagnostics.com/antimicrobial-susceptibility-testing.html.
About Creative Diagnostics
Headquartered in New York, Creative Diagnostics is a consulting and experimental  
service provider specializing in virology and microbiology. The company provides  
comprehensive solutions to conquer obstacles in virology and microbiology research,  
from high-security infrastructure provision, biosafety regulation elucidation, to  
expert viral system assistance.