Osteogenesis Imperfecta in Children - Causes, symptoms & Treatment - Presentation-TrishlaOrtho
                     Osteogenesis 
Imperfecta in 
C hildren
Causes, symptoms & Treatment
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What is Osteogenesis m/
Imperfecta in children?
Osteogenesis Imperfecta is a bone 
disease, and It is a rare disease in 
which baby bones get broken easily. 
And its also known as a brittle bone 
disease.
• It’s a genetic bone disease
• It has been present since birth.
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Causes of Osteogenesis m/
Imperfecta :
This is a Genetic disease. In which one 
of the genes have the problem of  Type 
1 Collagen, and It is mostly found in 
teeth, ligaments, and bones where the 
children will not have sufficient good 
quality collagen, which will lead to 
fragile bones that break very easily.
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Symptoms of Osteogenesis m/
Imperfecta in children?
Each child has different types of symptoms in 
their body.
• Curved spine.
• Hearing loss
• Soft & Discoloration of teeth
• Muscle weakness
• Deformity of bone, especially in the leg        
   and arm 
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Types of Osteogenesis m/
Imperfecta (OI) –
Type 1:
This is the most common form of OI & 
mildest one. In this variety, bones get 
fractured easily and get muscles 
weak.
Type 2:
In this variety, babies have very little 
chance of survival and die at a young 
age.
 Types of Osteogenesis 
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m/
Imperfecta (OI) –
Type 3:
Either Baby born with fractures and 
bones get fractured very easily,and 
children have hearing problems 
with poor muscle development.
Type 4:
This is moderately severe. This 
variety is between type 1 & 3. Near 
normal coloured sclera in eye. Mild 
to moderate bony deformity.
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Treatment m/
• Physical exercise increases 
strength, flexibility, and range of 
motion
• Treatment depends on the 
child's symptoms, age, and 
general health; the child
• It aims to prevention and 
treatment of fractures & correct 
deformity etc.
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