Bioprinting
                     BIOPRINTING
What Is Bioprinting?
 3D Bioprinting is a form of additive manufacturing that uses cells and 
other biocompatible materials as “inks”, also known as bioinks, to 
print living structures layer-by-layer which mimic the behavior of 
natural living systems.
Source: www.allevi3d.com
How does 3D bioprinting work?
 3D bioprinting starts with a model of a structure, which is recreated 
layer-by-layer out of a bioink either mixed with living cells, or seeded 
with cells after the print is complete. 
Source: www.allevi3d.com
Analyze the geometry of the model
 3D model file is then fed into a slicer a specialized kind of computer 
program which analyzes the geometry of the model and generates a 
series of thin layers, or slices, which form the shape of the original 
model when stacked vertically. 
Source: www.allevi3d.com
Final stage
 Once a model is sliced, the slices are transformed into path data, 
stored as a g-code file, which can be sent to a 3D bioprinter for 
printing.
 Once all of the g-code commands are completed, the print is done 
and can be cultured or seeded with cells as part of a biostudy.
Source: www.allevi3d.com
Why is bioprinting important?
 The scientific community has already succeeded in bringing together 
multidisciplinary teams of researchers, physicians, and engineers to 
take on the biggest challenges to human health, and 3D bioprinting is 
an exciting new tool with the potential to eliminate the organ 
transplant waiting list.
Source: www.allevi3d.com
Bioprinting For Pharmaceutical Development
 For pharmaceutical development, 3D bioprinting offers a means of 
testing drugs faster, at a lower cost, and with better biological 
relevance to humans than animal testing.
Source: www.allevi3d.com
Bioprinting For Biomedical Devices 
 In the biomedical devices field, 3D bioprinting has enabled new 
developments such as sugar stents to help surgeons join veins with 
fewer complications, and systems for improved drug delivery, among 
others.
Source: www.allevi3d.com
Bioprinting For Organ Replacement
 As bioprinting evolves, it will become possible to use a patient’s own 
cells to 3D print skin and bone grafts, organ patches, and even full 
replacement organs.
Source: www.allevi3d.com
Bioprinting For target treatments 
 Personalized and regenerative medicine continue to grow in 
popularity, and 3D bioprinting will give doctors and researchers the 
tools to better target treatments and improve patient outcomes.
Source: www.allevi3d.com
Challenges of 3D bioprinting
 The most burning issue is the question of regulation as an up-to-date, 
comprehensive set of rules for bioprinting has not yet been drafted. 
 That might be very dangerous since the black market for printed 
organs might thrive the most if regulations are not sufficiently strict 
and precise.
Source: www.allevi3d.com