The global Missile Defense System Market is estimated to reach approximately USD 32.80 billion in 2025 and is projected to grow to USD 67.90 billion by 2035, registering a CAGR of 7.5% during the forecast period. The market is witnessing steady expansion driven by rising geopolitical tensions, increasing defense budgets, and the growing need for advanced protection against ballistic and cruise missile threats. Missile defense systems are critical for safeguarding national security, protecting strategic assets, and ensuring operational readiness across land, air, and naval domains. The integration of artificial intelligence (AI), Internet of Things (IoT), and automation is transforming missile defense architectures into intelligent, network-centric systems capable of real-time threat detection, interception, and decision-making. Digital transformation in defense infrastructure, combined with advancements in radar systems, interceptor technologies, and command-and-control networks, is further accelerating market growth globally.