functional foods and nutraceuticals
                     
Nanofabrication technology 
for  nutraceuticals
New Technologies Report  
Date: 22th November, 
2023
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INTRODUCTION
The near-atomic manipulation of matter to produce new materials, structures, and devices is known as  
nanotechnology. The method promises advancements in science across domains, including  
manufacturing, consumer goods, energy, materials, and medicine.
Nanotechnology is a promising and fast-growing field in food, beverage and nutraceutical industries.
With an ever-increasing demand for products with health benefits, nutraceuticals are becoming popular. 
 Nutraceuticals contain several bioactive compounds that are susceptible to degradation during 
handling  and processing.
Nanotechnology, or nanofabrication of bioactive compounds with better delivery strategies to improve 
the  efficacy and stability of the nutraceuticals.
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Nanofabrication for 
nutraceuticals:
Advances in Nano-formulation processes reduce the limitations of bioactive molecules such 
as  bioavailability, specificity, and solubility. This provides new insights into the discovery of 
novel  materials, which are primarily suitable for various biomedical applications.
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Advantages:
Enhanced solubility, stability, bioavailability and efficacy of nutraceticals with encapsulation
of
nutraceuticals by nanoparticles.
One of the effective methods has been encapsulation with the “generally recognized as
safe”
(GRAS) nanomaterials which promote sustained release of the functional ingredients of
the  nutraceuticals in the body, simultaneously also increasing their nutritional quality and 
stability
Nano emulsions are extremely small, transparent or translucent droplet emulsions. The size of the
droplets varies from 50 to 200 nm which makes it easier for absorption.
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Disadvantages:
The main concern about human exposure to nanoparticles is that they can enter the body through
several mechanisms such as digestion, inhalation, or skin absorption. Nanoparticles may enter the  
circulation after absorption and settle in various organs such as the brain, or they may provoke  
immunological reactions.
Nanomaterials have unique qualities, such as a large surface area, which makes them more 
chemically
active than bulk materials, allowing them to engage in the majority of biological reactions that 
might  be damaging to human health or the environment.
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Different delivery system with 
nanotechnology:
Carbohydrate/Polysaccharides Delivery 
Systems  Protein-Based Delivery Systems
Lipid-Based Nano Delivery 
Systems  Nanoemulsions
Nanoliposomes  
Nanostructured Lipid 
Carrier  Nanogels [1]
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REFERENCES
1. htt
ps://www.mdpi.com/2306-5354/9/9/47
8
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THANK YOU
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