Hexamethyldisilazane (HMDS) remains a niche but essential chemical, especially within the semiconductor industry where it is used to prime silicon wafer surfaces for photolithography. In 2025, global HMDS production is shaped by steady demand from semiconductor fabrication, coatings, and pharmaceutical synthesis. The market is estimated to be valued around USD 530 million, with projections pointing to growth towards USD 660 million by 2031–2033, at a CAGR of 3%–6%.