In 2025, the global production of refrigerant-grade isobutane (R-600a) is experiencing steady growth. This uptick is driven by the increasing demand for low-global warming potential (GWP) refrigerants as industries transition away from high-GWP substances. Manufacturers are expanding capacities to meet this demand, particularly in regions with stringent environmental regulations. The price of R-600a has seen fluctuations in 2025, influenced by factors such as feedstock availability and regulatory changes. In North America, prices experienced a modest increase due to heightened demand and production adjustments. Conversely, European markets observed moderate price variations, affected by seasonal demand and economic factors.